Advanced Science, EarlyView.A multifunctional injectable microsphere system is fabricated via UV‐assisted microfluidic cross‐linking, integrating nanozyme‐based ROS scavenging, sustained dexamethasone release, and stem cell delivery. Upon IA injection, the microspheres adapt to joint stress, suppress inflammation, and promote cartilage regeneration, offering a minimally invasive ...
Xiaochen Feng +10 more
wiley +1 more source
The Role of Scavenger Receptor BI in Sepsis. [PDF]
Int J Mol SciHao D, Xue JY, Wang Q, Guo L, Li XA.
europepmc +1 more source
Granulocyte-derived extracellular vesicles activate monocytes and are associated with mortality in intensive care unit patients [PDF]
, 2018 Adelman, Avril +3 more
core +1 more source
Advanced Science, EarlyView.CircMT‐RNR2 promotes wound healing by enhancing fibroblast proliferation, migration, contraction, and extracellular matrix (ECM) production. It sustains mitochondrial redox balance by stabilizing the antioxidant protein PRDX3, thereby reducing ROS‐induced damage. In diabetic foot ulcers, hypoxia, hyperglycemia, and reduced FGF2 and EGF expression lower
Guanglin Niu +13 more
wiley +1 more source
Microfluidic Generation of Oxidized Phospholipid Gradients in Supported Lipid Bilayers to Examine Scavenger Receptor Interactions. [PDF]
Anal ChemBerger BA +3 more
europepmc +1 more source
Advanced Science, EarlyView.The Cu‐Zn3In2S6 photocatalyst (Cu‐ZISV) with asymmetric Cu‐SV‐Zn sites was designed and synthesized to boost peroxymonosulfate (PMS) activation kinetics. The side‐on photo‐Fenton‐like reaction by the asymmetric Cu‐SV‐Zn site accelerated PMS activation and pollutant degradation, and the first‐order kinetic constant of Cu‐ZISV increased by 4.87 times ...
Jiaqi Hu +7 more
wiley +1 more source
"Affimer" synthetic protein scaffolds block oxidized LDL binding to the LOX-1 scavenger receptor and inhibit ERK1/2 activation. [PDF]
J Biol Chem, 2023 Roper BWR +13 more
europepmc +1 more source
Thermally Gated Dual‐Cascade Nanozyme for Enhanced Mild‐Temperature Photothermal Therapy
Advanced Science, EarlyView.A thermo‐responsive cascade nanozyme (Ru‐GOx‐PNN) synergistically enhances mild photothermal therapy by dual suppression of HSP70 through ROS‐induced lipid peroxidation and ATP depletion. This intelligent system effectively overcomes thermotolerance and amplifies apoptosis, offering a safe and precise strategy for tumor treatment.
Shuyu Wang +7 more
wiley +1 more source
PTEN inhibits scavenger receptor-mediated phagocytosis of methicillin-resistant Staphylococcus aureus. [PDF]
ImmunohorizonsFaneuff EE +12 more
europepmc +1 more source
Periodontitis Induces B Cell‐Macrophage Crosstalk to Exacerbate Glucose Dysregulation in Obesity
Advanced Science, EarlyView.In obesity, periodontitis exacerbates hyperglycemia and exhibits a liver‐centric preference for glucose regulation. This occurs through a periodontitis‐driven circuit between pathogenic B cells and hepatic macrophages. Their reciprocal expansion, orchestrated by the NLRP3/IL‐18 signaling pathway, amplifies metabolic inflammation and disrupts glucose ...
Wen‐Zhen Lin +19 more
wiley +1 more source