Results 81 to 90 of about 486,419 (221)
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto+2 more
wiley +1 more source
Hole Scavenging and Photo-Stimulated Recombination of Electron-Hole Pairs in Aqueous TiO2 Nanoparticles [PDF]
It is shown that 532 nm and 1064 nm laser photoexcitation of trapped electrons generated by 355 nm photolysis of aqueous titania (TiO2) nanoparticles causes rapid photobleaching of their absorbance band in the visible and near IR. This photobleaching occurs within the duration of the laser pulse (3 ns FWHM); it is caused by photoinduced electron ...
arxiv
Melanoma cell spheroid engraftment is optimized in the chicken chorioallantoic membrane overcoming the complexity of other in vivo models. Using this model, greater penetration of cerium oxide nanoparticles (nanoceria) functionalized with heparin in spheroids is observed via enhancement of vascularization than nanoceria alone.
Lu Fu+5 more
wiley +1 more source
Local Clustering and Global Spreading of Receptors for Optimal Spatial Gradient Sensing [PDF]
Spatial information from cell-surface receptors is crucial for processes that require signal processing and sensing of the environment. Here, we investigate the optimal placement of such receptors through a theoretical model that minimizes uncertainty in gradient estimation.
arxiv +1 more source
High glucose‐ and acid‐responsive hydrogel with dynamic covalent bond solubilized with flavonoids (Gel‐Flavonoids) is designed for diabetic wound healing. The Gel‐Flavonoids adapt to irregular wound shapes and release antioxidants in high‐glucose environments, effectively reducing reactive oxygen species.
Qiang Zeng+9 more
wiley +1 more source
Covalent Organic Frameworks for Photocatalysis
This review provides an overview of recent advances in covalent organic frameworks (COFs) for photocatalysis, focusing on sustainable energy applications like water splitting, hydrogen peroxide generation, and CO2 and N2 reduction. It discusses design principles, structure‐function relationships, challenges in COF photocatalysis, and strategies to ...
Bikash Mishra+6 more
wiley +1 more source
Off‐The‐Shelf Multivalent Nanoconjugate Cancer Vaccine Rescues Host Immune Response against Melanoma
A star‐shaped cross‐linked polyglutamate (StCl) nanocarrier delivers melanoma‐associated peptide antigens via redox‐responsive linkers, inducing lymph node‐targeted antigen presentation. The nanoconjugate activates dendritic cells, promotes effector T‐cell responses, and enables tumor regression even in humanized patient‐derived preclinical models ...
Liane IF Moura+19 more
wiley +1 more source
Photo‐Induced Bandgap Engineering of Metal Halide Perovskite Quantum Dots In Flow
This work presents a photochemical synthetic route for bandgap engineering of metal halide perovskite quantum dots. Utilizing a material‐efficient microfluidic platform, the underlying mechanism of the photo‐induced anion exchange reaction (PIAER) of metal halide perovskite quantum dots is unveiled and first instance of the PIAER‐enabled synthesis of ...
Pragyan Jha+9 more
wiley +1 more source
SR-BI-directed HDL-cholesteryl ester hydrolysis
We have examined the metabolic fate of HDL cholesteryl ester (CE) delivered to cells expressing scavenger receptor class B type I (SR-BI). Comparison of SR-BI with a related class B scavenger receptor, CD36, showed a greater uptake and a more rapid and ...
Margery A. Connelly+3 more
doaj
Simple approach for calculating the binding free energy of a multivalent particle [PDF]
We present a simple yet accurate numerical approach to compute the free energy of binding of multivalent objects on a receptor-coated surface. The method correctly accounts for the fact that one ligand can bind to at most one receptor. The numerical approach is based on a saddle-point approximation to the computation of a complex residue.
arxiv +1 more source