Results 131 to 140 of about 44,698 (301)

T cell stimulation and expansion by SunTag-based clustering of anti-CD3/CD28 scFv

, 2020
Kunhong Zhong, Zhiyong Liu, Hongjian Li, Shasha Zhao, Yuelong Wang, Wenhao Guo, Xi Zheng, Hui Yang, Gang Guo, Liangxue Zhou, Jianguo Xu, Aiping Tong   +11 more
openalex   +2 more sources

Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells

Allergy, EarlyView.
We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller, Julia Hambach, Alessa Zoe Schaffrath, Thomas Eden, Sophia Cichutek, Anna Josephine Gebhardt, Natalie Tode, Ronald Maitschke‐Rajasekharan, Philipp Lewe, Sharon Qi, Susanne Witt, Marie Eggers, Nicola M. Tomas, Friedrich Haag, Friedrich Koch‐Nolte, Boris Fehse, Kristoffer Riecken   +16 more
wiley   +1 more source

Transgenic Chickens Expressing the 3D8 Single Chain Variable Fragment Protein Suppress Avian Influenza Transmission

Scientific Reports, 2017
The 3D8 single chain variable fragment (scFv) is a mini-antibody that causes unusual sequence-independent nuclease activity against all types of nucleic acids.
Sung June Byun, Seong-su Yuk, Ye-Jin Jang, Hoonsung Choi, Mi-Hyang Jeon, TO Erdene-Ochir, Jung-Hoon Kwon, Jin-Yong Noh, Jeom Sun Kim, Jae Gyu YOO, Chang-Seon Song   +10 more
doaj   +1 more source

International effort toward a SSR-based linkage map for C. clementina : [P128] [PDF]

, 2008
Following the difficulties encountered for assembling a 1.2 x sequencing of the highly heterozygous sweet orange genome, the International Citrus Genomic Consortium (ICOC) decided to estab1ish the first reference sequence of a whole nuclear citrus genome
Billot, Claire, Chen, Chunxian, Costantino, Gilles, Federici, Claire T., Ferrer, R.M., Froelicher, Yann, Gmitter, Frederick G. Jr., Kacar, A.Yildiz, Lotfy, Samia, Luro, François, Morillon, Raphaël, Mu, L., Navarro, Luis, Ollitrault, Frédérique, Ollitrault, Patrick, Roose, Mikeal L., Talon, Manuel, Terol, Javier F.   +17 more
core  

Single Chain Fragment Variable (scFv) corresponding to a novel epitope within HCV envelope protein restricts virus entry into hepatocytes [PDF]

, 2023
Soma Das, Soma Das, P. Behera, Dipeshwari J. Shewale, Janhavi Bodele, Saumitra Das, Saumitra Das, Anjali A. Karande   +7 more
openalex   +1 more source

Sperm Sexing in Selected Animals and Humans: Methods, Applications, and Future Prospects

Andrology, EarlyView.
ABSTRACT Background Sperm sexing is a technique that enables the selection of offspring sex by sorting spermatozoa based on their sex chromosomes. This technology has gained increasing attention due to its potential applications in both animal breeding and human‐assisted reproduction.
Domrazek Kinga, Jurka Piotr
wiley   +1 more source

Enhancement of hERG channel activity by scFv antibody fragments targeted to the PAS domain [PDF]

, 2016
Carol A. Harley, Greg Starek, David K. Jones, Andreia S. Fernandes, Gail A. Robertson, João H. Morais‐Cabral   +5 more
openalex   +1 more source

Development of novel detection system for sweet potato leaf curl virus using recombinant scFv [PDF]

, 2020
Sang-Ho Cho, Eui‐Joon Kil, Sungrae Cho, Hee‐Seong Byun, Eun-Ha Kang, Hong-Soo Choi, Mi‐Gi Lee, Jong-Suk Lee, Young-Gyu Lee, Sukchan Lee   +9 more
openalex   +1 more source

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz, Sophie Sprenger, Olga Schweigert, Sanika Mohagaonkar, Matti Walsdorff, Tanja Zeller, Filip Berisha, Viacheslav O. Nikolaev, Sergei D. Rybalkin   +8 more
wiley   +1 more source

Generation of a recombinant single-chain variable fragment (scFv) targeting 5-methyl-2'-deoxycytidine [PDF]

, 2009
Masayuki Ohshima, T Tadakuma, Hideki Hayashi, Ken‐ichiro Inoue, Kunihiko Itoh   +4 more
openalex   +1 more source