Results 81 to 90 of about 128,417 (336)

Reprogramming diminishes retention of Mycobacterium leprae in Schwann cells and elevates bacterial transfer property to fibroblasts [v2; ref status: indexed, http://f1000r.es/280]

F1000Research, 2013
Background: Bacterial pathogens can manipulate or subvert host tissue cells to their advantage at different stages during infection, from initial colonization in primary host niches to dissemination. Recently, we have shown that Mycobacterium leprae (ML),
Toshihiro Masaki, Aidan McGlinchey, Simon R. Tomlinson, Jinrong Qu, Anura Rambukkana   +4 more
doaj   +1 more source

FAK is required for axonal sorting by Schwann cells [PDF]

, 2007
Signaling by laminins and axonal neuregulin has been implicated in regulating axon sorting by myelin-forming Schwann cells. However, the signal transduction mechanisms are unknown.
Brophy, Peter J., Grant, Seth G., Grove, Matthew, Komiyama, Noboru H., Nave, Klaus-Armin, Sherman, Diane L.   +5 more
core   +3 more sources

Microfluidic Spinning of PEDOT:PSS Microfibers for Nerve Guidance Conduits

Advanced Materials Technologies, EarlyView.
This publication explores the fabrication of microfluidically spun PEDOT:PSS microfibers for conductive nerve guidance conduits (NGCs). It details the spinning process, fiber characterization, and biocompatibility assessment. The study highlights the fibers' mechanical and electrical properties, non‐cytotoxicity, and potential for nerve regeneration or
Matthias Geiger, Judith Frank, Felix Schmitz, Richard Paul, Sebastian Bernhard Rauer, Stanislav Koulchitsky, Angelika Lampert, John Linkhorst, Matthias Wessling   +8 more
wiley   +1 more source

Dynamics of cell-type transition mediated by epigenetic modifications [PDF]

arXiv, 2023
Maintaining tissue homeostasis requires appropriate regulation of stem cell differentiation. The Waddington landscape posits that gene circuits in a cell form a potential landscape of different cell types, wherein cells follow attractors of the probability landscape to develop into distinct cell types.
arxiv  

Tip cell overtaking occurs as a side effect of sprouting in computational models of angiogenesis [PDF]

BMC Systems Biology 2015, 9:86, 2015
During angiogenesis, endothelial cells compete for the tip position during angiogenesis: a phenomenon named tip cell overtaking. It is still unclear to what extent tip cell overtaking is a side effect of sprouting or to what extent a biological function.
arxiv   +1 more source

Degeneration and regeneration of peripheral nerves: role of thrombin and its receptor PAR-1 [PDF]

, 2017
The peripheral nervous system has a striking regeneration potential and after damage extensive changes in the differentiation state both of the injured neurons and of the Schwann cells are observed.
Artico, M., Ciraci, V., Fabrizi, C., Fumagalli, L., Leone, S., Maras, B., Pompili, E., Schininà, M. E.   +7 more
core  

Insights on Advances in 3D Bioprinting for Peripheral Nerve Regeneration

Advanced Therapeutics, EarlyView.
Peripheral nerve injury is a common condition due to trauma that significantly impacts the life of the affected individual. This review explores the anatomy, classification, and pathophysiology of peripheral nerve injuries. It also discusses various types of nerve conduits and presents a detailed review of 3D bioprinted nerve conduits used in both in ...
Nasera Rizwana, Samartha M C, Ashwath Acharya, Goutam Thakur, Manasa Nune, Vipul Agarwal   +5 more
wiley   +1 more source

Tractions and stress fibers control cell shape and rearrangements in collective cell migration [PDF]

Phys. Rev. X 10, 011016 (2020), 2019
Key to collective cell migration is the ability of cells to rearrange their position with respect to their neighbors. Recent theory and experiments demonstrated that cellular rearrangements are facilitated by cell shape, with cells having more elongated shapes and greater perimeters more easily sliding past their neighbors within the cell layer. Though
arxiv   +1 more source

Advances in Microfluidic Cochlea‐On‐A‐Chip

Advanced Science, EarlyView.
This review systematically examines diverse cell sources for inner ear organoids and outlines stepwise induction protocols. Furthermore, it discusses current applications and prospective developments of cochlea‐on‐a‐chip technologies in areas such as deafness modeling, mechanistic studies, and drug evaluation, with particular focus on gene‐therapy drug
Tian Shen, Shanying Han, Weiwei He, Wen Yang, Xinghua Tang, Xiaolong Zhao, Xinghong Liu, Zhenhua Shao, Lin Cheng, Yu Zhao, Jiangang Fan   +10 more
wiley   +1 more source

Understanding and treating ejaculatory dysfunction in men with diabetes mellitus

Andrology, Volume 11, Issue 2, Page 379-398, February 2023., 2023
Abstract Diabetes mellitus is a rapidly rising metabolic disorder with important systemic complications. Global figures have demonstrated the prevalence of diabetes mellitus has almost quadrupled from 108 million in 1980 to 422 million in 2014, with a current prevalence of over 525 million.
Ankit Desai, Runzhi Chen, Axel Cayetano, Channa N. Jayasena, Suks Minhas   +4 more
wiley   +1 more source