Results 11 to 20 of about 5,167 (220)

Comparative venom gland transcriptome analysis of the scorpion Lychas mucronatus reveals intraspecific toxic gene diversity and new venomous components [PDF]

BMC Genomics, 2010
Background Lychas mucronatus is one scorpion species widely distributed in Southeast Asia and southern China. Anything is hardly known about its venom components, despite the fact that it can often cause human accidents.
Zhijian Cao, Yingliang Wu, Zhiyong Di, Yawen He, Yibao Ma, Ruiming Zhao, Wenxin Li   +6 more
doaj   +4 more sources

Oral Acute Toxicity and Genotoxicity of Heteroctenus junceus Scorpion Venom. [PDF]

Vet Med Sci
The Heteroctenus junceus scorpion venom is a very popular natural extract used in traditional medicine in Cuba. In clinically relevant experimental settings, scorpion venom does not induce general toxicity or an increase in the frequency of micronucleus formation in erythrocytes.
Díaz-García A, Ruiz-Fuentes JL, Mejias Medina S, Zapata Guajardo N, Ross Skarneo C.   +4 more
europepmc   +2 more sources

Animal Venoms as Peptide Libraries for the Discovery of Antiglioblastoma Agents. [PDF]

Biochem Res Int
Glioblastoma is one of the most aggressive and widely recognized types of brain tumors, characterized by significant cellular and molecular diversity and an inherently aggressive nature. The treatment remains highly challenging, with limited effectiveness and persistently low survival rates.
Santiago LR, Pinos Tamayo EA, Moreira Dos Santos D, Kim B, Almeida JR, Ribeiro RIMA.   +5 more
europepmc   +2 more sources

SdPI, the first functionally characterized Kunitz-type trypsin inhibitor from scorpion venom. [PDF]

PLoS ONE, 2011
BACKGROUND: Kunitz-type venom peptides have been isolated from a wide variety of venomous animals. They usually have protease inhibitory activity or potassium channel blocking activity, which by virtue of the effects on predator animals are essential for
Ruiming Zhao, Hui Dai, Su Qiu, Tian Li, Yawen He, Yibao Ma, Zongyun Chen, Yingliang Wu, Wenxin Li, Zhijian Cao   +9 more
doaj   +1 more source

Acetylcholinesterase inhibitory potential of scorpion venom in Aedes aegypti (Diptera: Culicidae) [PDF]

Brazilian Journal of Biology, 2022
Scorpion venom contains a variety of neurotoxins which interact with ion channels and affect their activities. The present study was designed to evaluate the potential of scorpion venom as acetylcholinesterase (AChE) inhibitor by using Aedes aegypti as ...
N. Riaz, F. Zubair, N. Amjad, S. Ashraf, S. Asghar, M. Z. Awan, S. Javaid   +6 more
doaj   +1 more source

Mass-Spectrometry-Based Lipidome and Proteome Profiling of Hottentotta saulcyi (Scorpiones: Buthidae) Venom

Toxins, 2022
Scorpion venom is a complex secretory mixture of components with potential biological and physiological properties that attracted many researchers due to promising applications from clinical and pharmacological perspectives.
Parviz Ghezellou, Kevin Jakob, Javad Atashi, Alireza Ghassempour, Bernhard Spengler   +4 more
doaj   +1 more source

Scorpion Venom: Detriments and Benefits

Biomedicines, 2020
Scorpion venom may cause severe medical complications and untimely death if injected into the human body. Neurotoxins are the main components of scorpion venom that are known to be responsible for the pathological manifestations of envenoming.
Shirin Ahmadi, Julius M. Knerr, Lídia Argemi, Karla C. F. Bordon, Manuela B. Pucca, Felipe A. Cerni, Eliane C. Arantes, Figen Çalışkan, Andreas H. Laustsen   +8 more
doaj   +1 more source

Molecular Cloning and Functional Identification of the Antimicrobial Peptide Gene Ctri9594 from the Venom of the Scorpion Chaerilus tricostatus

Antibiotics, 2021
Scorpion venom is a mixture of bioactive peptides, among which neurotoxins and antimicrobial peptides serve especially vital functions. Scorpion venom peptides in Buthidae species have been well described, but toxic peptides from non-Buthidae species ...
Dangui He, Zhijian Cao, Ruhong Zhang, Wenhua Li   +3 more
doaj   +1 more source

Antimicrobial peptides from scorpion venoms

Toxicon, 2014
The need for new antimicrobial agents is becoming one of the most urgent requirements in modern medicine. The venoms of many different species are rich sources of biologically active components and various therapeutic agents have been characterized including antimicrobial peptides (AMPs).
Harrison, Patrick L., Abdel-Rahman, Mohamed A., Miller, Keith, Strong, Peter N.   +3 more
openaire   +2 more sources

Dramatic expansion of the black widow toxin arsenal uncovered by multi-tissue transcriptomics and venom proteomics. [PDF]

, 2014
BackgroundAnimal venoms attract enormous interest given their potential for pharmacological discovery and understanding the evolution of natural chemistries.
Ayoub, Nadia A, Clarke, Thomas H, Garb, Jessica E, Haney, Robert A, Hayashi, Cheryl Y   +4 more
core   +2 more sources