Scorpion Venom: Detriments and Benefits [PDF]
Biomedicines, 2020 Scorpion venom may cause severe medical complications and untimely death if injected into the human body. Neurotoxins are the main components of scorpion venom that are known to be responsible for the pathological manifestations of envenoming.
Shirin Ahmadi +8 more
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Exploring the potential of Brazilian Amazonian scorpion venoms: A comprehensive review of research from 2001 to 2021 [PDF]
Toxicon: XThe Amazon biome is home to many scorpion species, with around two hundred identified in the region. Of these, forty-eight species have been reported in Brazil so far and six of them are of medical importance: Tityus apiacas, T. metuendus, T. obscurus, T.
Joel Ramanan da Cruz +2 more
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Pioneering Comparative Proteomic and Enzymatic Profiling of Amazonian Scorpion Venoms Enables the Isolation of Their First α-Ktx, Metalloprotease, and Phospholipase A2 [PDF]
ToxinsScorpionism is a growing public health concern in Brazil, with the Amazon region presenting the highest mortality rates but remaining understudied, especially regarding local scorpion venoms composition.
Karla C. F. Bordon +9 more
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Scorpions from Mexico: From Species Diversity to Venom Complexity [PDF]
Toxins, 2015 Scorpions are among the oldest terrestrial arthropods, which are distributed worldwide, except for Antarctica and some Pacific islands. Scorpion envenomation represents a public health problem in several parts of the world.
Carlos E. Santibáñez-López +3 more
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Scorpion Venom and the Inflammatory Response [PDF]
Mediators of Inflammation, 2010 Scorpion venoms consist of a complex of several toxins that exhibit a wide range of biological properties and actions, as well as chemical compositions, toxicity, and pharmacokinetic and pharmacodynamic characteristics.
Vera L. Petricevich
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In vitro determination of the efficacy of scorpion venoms as anti-cancer agents against colorectal cancer cells: a nano-liposomal delivery approach [PDF]
International Journal of Nanomedicine, 2017 Abdulrahman K Al-Asmari,1 Zabih Ullah,1 Ali Al Balowi,2 Mozaffarul Islam1 1Department of Research, Prince Sultan Military Medical City, Riyadh, 2Department of Pharmacy, King Fahad Armed Forces Hospital, Jeddah, Saudi Arabia Abstract: The use of ...
Al-Asmari AK +3 more
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Animal Venoms as Peptide Libraries for the Discovery of Antiglioblastoma Agents. [PDF]
Biochem Res IntGlioblastoma is one of the most aggressive and widely recognized types of brain tumors, characterized by significant cellular and molecular diversity and an inherently aggressive nature. The treatment remains highly challenging, with limited effectiveness and persistently low survival rates.
Santiago LR +5 more
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Recombinant expression and antigenicity of two peptide families of neurotoxins from Androctonus sp.
Journal of Venomous Animals and Toxins including Tropical Diseases, 2022 Background: Scorpion neurotoxins such as those that modify the mammalian voltage-gated sodium ion channels (Nav) are the main responsible for scorpion envenomation. Their neutralization is crucial in the production of antivenoms against scorpion stings.
Samuel Cardoso-Arenas +7 more
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Antibiotics, 2023 Scorpion venoms have long captivated scientific researchers, primarily due to the potency and specificity of the mechanism of action of their derived components. Among other molecules, these venoms contain highly active compounds, including antimicrobial
Sara Nasr +7 more
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Scorpion Species with Smaller Body Sizes and Narrower Chelae Have the Highest Venom Potency
Toxins, 2022 Scorpionism is a global health concern, with an estimation of over one million annual envenomation cases. Despite this, little is known regarding the drivers of scorpion venom potency.
Alannah Forde +3 more
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