Results 41 to 50 of about 3,672 (169)

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, Volume 40, Issue 8, Page 4759-4791, August 2026.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

A comprehensive review on phytochemistry, pharmacology, and flavonoid biosynthesis of Scutellaria baicalensis

Pharmaceutical Biology, 2018
Context: Scutellaria baicalensis Georgi (Lamiaceae) is a popular medicinal plant. Its roots are used as the famous traditional Chinese medicine Huang-Qin, which is recorded in Chinese Pharmacopoeia, European Pharmacopoeia, and British Pharmacopoeia ...
Zi-Long Wang, Shuang Wang, Yi Kuang, Zhi-Min Hu, Xue Qiao, Min Ye   +5 more
doaj   +1 more source

Research on the Mechanism of Natural Products Acting on Chronic Obstructive Pulmonary Disease

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
This figure illustrates that approximately 80 natural compounds exert therapeutic effects against chronic obstructive pulmonary disease by targeting pathological mechanisms such as airway inflammation, oxidative stress, airway remodeling, mucus hypersecretion, emphysema, protease–antiprotease imbalance, apoptosis, and autophagy.
Shuna Wei, Xiaoju Liu
wiley   +1 more source

SbWRKY75- and SbWRKY41-mediated jasmonic acid signaling regulates baicalin biosynthesis

Frontiers in Plant Science, 2023
IntroductionScutellaria baicalensis Georgi is a traditional Chinese medicinal plant with broad pharmacological activities whose main active ingredient is the flavonoid baicalin.
Shiyuan Fang, Shiyuan Fang, Chen Zhang, Chen Zhang, Shi Qiu, Ying Xiao, Kaixian Chen, Zongyou Lv, Wansheng Chen, Wansheng Chen   +9 more
doaj   +1 more source

Recent Advances in the Use of Natural Deep Eutectic Solvents for Natural Product Sample Preparation: Focus on Purification, Characterization, and Sustainability

Journal of Separation Science, Volume 49, Issue 7, July 2026.
ABSTRACT This review examines recent advances in the use of natural deep eutectic solvents (NaDES) for natural product sample preparation, with emphasis on extraction, purification, analytical compatibility, and sustainability. NaDES emerge as versatile, tunable, and biocompatible media that enhance the recovery and stability of diverse phytochemicals ...
Valeria Cedeño‐Fierro, Juan Felipe Grisales‐Mejía, Harlen Gerardo Torres Castañeda, Jose A. Mendiola   +3 more
wiley   +1 more source

Herbal hydrogel incorporating Scutellaria baicalensis Georgi carbon dots and baicalein for antibacterial, anti-inflammatory, and wound healing applications

Materials & Design
Wound infection and excessive accumulation of reactive oxygen species (ROS) lead to inflammation, hindering wound healing. Baicalein (BAI) and baicalin (BA) coexist in Scutellaria baicalensis Georgi, with baicalein being one of the most abundant ...
Yuan Zhang, Ruinan Wang, Hengping Wang, Haiming Cheng, Huiyan Wang   +4 more
doaj   +1 more source

Targeting EZH2 in Cancer: From Molecular Mechanisms to Clinical Translation

MedComm – Oncology, Volume 5, Issue 2, June 2026.
The abnormal overexpression or gain‐of‐function mutations of EZH2 play a significant role in cancer occurrence and progression, highlighting the importance and potential of EZH2 as a cancer biomarker. Therefore, screening for effective and safe small‐molecule inhibitors, degraders, and natural compounds targeting EZH2 through preclinical cancer models ...
Xi Zhong, Jieni Li, Mingxuan Pan, Xiaoxue Ke, Hongjuan Cui   +4 more
wiley   +1 more source

Sparassis crispa and a Bioactive Compound Therein, Ergosterol, Were Effective in Preventing Acetylcholinesterase Inhibition In Vitro and In Vivo

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Sparassis crispa extract exhibited acetylcholinesterase inhibitory and antioxidant activities, and ergosterol was identified as a major bioactive sterol. In a TMT‐induced mouse model, both the extract and ergosterol improved spatial working memory and learning retention while reducing brain AChE activity and lipid peroxidation.
Chan Kyu Park, Gyumin Kang, Soo Jung Choi, Yoon Seo Lee, Eui‐Cheol Shin, Hyo In Kim, Jinbong Park, Nam Su Oh, Hyung Taek Cho, Tae Gyun Kim, Jeong Hoon Pan, Dong‐Hoon Shin, Young‐Jun Kim, Jae Kyeom Kim   +13 more
wiley   +1 more source

Scutellaria baicalensis Georgi extracts and its active compound baicalin promote tomato seedling growth

Vegetable Research
Excessive use of chemical fertilizers and pesticides causes pollution of soil, water, and the atmosphere. Biostimulants are derived from natural sources, which can help plants absorb nutrients and promote plant development.
Genzhong Liu, Jinyang Xin, Chaoyu Li, Mingxuan Ma, Jiaojiao Fan, Chenyu Xu, Jia Li, Dong Fang, Fangfang Ma, Zhilong Bao   +9 more
doaj   +1 more source

Water deficit affected flavonoid accumulation by regulating hormone metabolism in Scutellaria baicalensis Georgi roots. [PDF]

PLoS ONE, 2012
The content of flavonoids especially baicalin and baicalein determined the medical quality of Scutellaria baicalensis which is a Chinese traditional medicinal plant.
Yuan Yuan, Yunjun Liu, Chong Wu, Shunqin Chen, Zhouyong Wang, Zhaochun Yang, Shuangshuang Qin, Luqi Huang   +7 more
doaj   +1 more source