Results 51 to 60 of about 3,672 (169)

Cancer Neuroscience: Innovative Conception and Emerging Strategy of Therapy

MedComm, Volume 7, Issue 4, April 2026.
In this review, we summarize nerve–cancer interactions and conclude two additional interactions, “perineural invasion” and “neuro‐microbic‐oncology.” Emphasizing the important role of nerves in tumor progression. The nervous system also contributes to the development of cancer comorbidities such as cancer depression and cognitive dysfunction.
Ting Wang, Zikai Dong, Yongfei Wang, Ziyi An, Siyuan Wang, Wei‐Lin Jin   +5 more
wiley   +1 more source

The effect of scutellaria baicalensis and its active ingredients on major depressive disorder: a systematic review and meta-analysis of literature in pre-clinical research

Frontiers in Pharmacology
Background: Scutellaria baicalensis, the dry root of scutellaria baicalensis georgi, is a traditional Chinese medicine with long. In clinic, scutellaria baicalensis is commonly used in prescription for the treatment of depression.
Ying Ma, Xun Zhou, Feng Zhang, Cuiyun Huang, Hong Yang, Wansheng Chen, Wansheng Chen, Xia Tao   +7 more
doaj   +1 more source

Ying‐Huang Oral Liquid Ameliorates Oxidative Stress in the Liver of Heat‐Stressed Broilers via KEAP1‐NRF2 and PINK1/Parkin Pathway

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
Protect liver health and enhance growth performance: ensure safer, higher‐quality meat, and improve economic efficiency in poultry production. Heat stress induces liver injury through oxidative stress, ferroptosis, and mitochondrial dysfunction. Yinhuang oral liquid (YOL) mitigates these effects via multi‐target mechanisms, including activation of the ...
Zi‐Hao Li, Jia‐Ci Cai, Yang Yang, Hui‐Lin Li, You Li, Shun Tian, Yong‐Ming He, Lu‐Ping Tang   +7 more
wiley   +1 more source

Baicalin Restores the Hypoglycemic Effect of Metformin by Regulating the Microbial Imidazole Propionate and Short‐Chain Fatty Acids

Phytotherapy Research, Volume 40, Issue 3, Page 1060-1073, March 2026.
Baicalin restores the hypoglycemic effect of metformin by decreasing the serum imidazole propionate. ABSTRACT Gut microbiota dysbiosis is implicated in metformin non‐response. This study aimed to investigate whether baicalin, a microbiota‐modulating flavonoid derived from Radix Scutellariae, could restore metformin sensitivity and explored the ...
Aiting Wang, Zenghui Miao, Bangrong Huang, Jiayu Zeng, Mingxia Yuan, Dan Yan   +5 more
wiley   +1 more source

Therapeutic Potential of Saikosaponins in MASLD and Cross‐Organ Protection: A Research Update

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
This review systematically outlines the multi‐target mechanisms of Saikosaponins (SSs) against MASLD, encompassing the regulation of lipid metabolism, insulin resistance, and inflammatory response. Furthermore, it highlights their novel cross‐organ protective effects on the cardiovascular, renal, and central nervous systems, providing therapeutic ...
Jiayao Xiong, Wanyan Tan, Ze Jin, Xiangyu Li, Yuting Chen, Wanting Xie   +5 more
wiley   +1 more source

Role of Chinese Botanical Drugs in the Adjuvant Treatment of Helicobacter pylori Infection: An Umbrella Review of the Evidence of Randomized Controlled Trials

International Journal of Clinical Practice, Volume 2026, Issue 1, 2026.
Aim To evaluate the quality of evidence, potential biases, and validity of all available meta‐analyses about the Chinese botanical drug treatment for the Helicobacter pylori (Hp) infection. Materials and Methods A comprehensive search of six electronic databases (PubMed, Embase, Web of Science, Cochrane Database of Systematic Reviews, CNKI, Wanfang ...
Yuege Yang, Xiaoyan Jiang, Baofu Lin, Chunhong Zhang, Donghou Liu, Marta Laranjo   +5 more
wiley   +1 more source

Mechanistic Elucidation of Yiqi Yangyin Qingre Decoction in Diabetic Nephropathy Therapy via Network Pharmacology and In Vivo Validation

Journal of Diabetes Research, Volume 2026, Issue 1, 2026.
Background Diabetic nephropathy (DN) is a serious microvascular complication of diabetes that urgently requires effective treatments with low toxicity. The traditional Chinese medicine formula Yiqi Yangyin Qingre decoction (YQYYQR) has demonstrated potential in alleviating DN, yet its pharmacological mechanism remains unclear.
Shujiao Zhang, Yiran Xie, Jingyi Tang, Xi Guo, Yuxin Hu, Yuzi Cai, Lin Wang, Xiaole Guo, Mengqi Zhou, Xu Wang, Yuanyuan Deng, Yu Ma, Yaoxian Wang, Wei Jing Liu, Alya Mashaal   +14 more
wiley   +1 more source

Wogonin a Promising Component of Scutellaria baicalensis: A Review on its Chemistry, Pharmacokinetics and Biological Activities

Archives of Pharmaceutical Sciences Ain Shams University, 2019
Scutellaria baicalensis Georgi (Huang-Qin or Chinese skullcap) is a native medicinal plant in China that is commonly used for the treatment of seizures, viral infections, and cancer.
Maha Hassanin, Mai Tolba, Marianne Tadros, Mohamed Elmazar, Abdel-Nasser Singab   +4 more
doaj   +1 more source

Endogenous salicylic acid shows different correlation with baicalin and baicalein in the medicinal plant Scutellaria baicalensis Georgi subjected to stress and exogenous salicylic acid. [PDF]

PLoS ONE, 2018
Salicylic acid (SA) is synthesized via the phenylalanine lyase (PAL) and isochorismate synthase (ICS) pathways and can influence the stress response in plants by regulating certain secondary metabolites. However, the association between SA and particular
Hu Su, Shurui Song, Xin Yan, Limin Fang, Bin Zeng, Youlin Zhu   +5 more
doaj   +1 more source

From Demyelination to Intervention: Natural Compounds as Emerging Therapeutic Targets in Multiple Sclerosis Neuroinflammation

Journal of Immunology Research, Volume 2026, Issue 1, 2026.
Multiple sclerosis (MS) is a chronic immune‐mediated inflammatory demyelinating disease of the central nervous system (CNS), characterized by multifocal lesions, axonal damage, and progressive neurological dysfunction, imposing a heavy burden on patients and healthcare systems.
Zhiyong Long, Qianyue Yang, Yonghe Wu, Lifei Wan, Liuting Zeng, Lingyun Sun, Poorani Gurumallesh   +6 more
wiley   +1 more source