Results 61 to 70 of about 3,672 (169)

A new antioxidant flavone glycoside from Scutellaria baicalensis Georgi

Natural Product Research, 2014
A new flavone glycoside, wogonin 7-O-β-d-ethylglucuronide (1), together with a new natural flavone glycoside baicalein 7-O-β-d-ethylglucuronide (2) and four known analogues, wogonoside (3), wogonin (4), oroxylin A 7-O-β-d-methylglucuronide (5) and oroxylin A (6), was isolated from the roots of Scutellaria baicalensis Georgi.
Meng-Hua, Wang, Lin-Zhen, Li, Jian-Bo, Sun, Fei-Hua, Wu, Jing-Yu, Liang   +4 more
openaire   +2 more sources

Chaiyin Granules Improve Acute Lung Injury by Regulating Gut Microbiota and Unsaturated Fatty Acid Mediated Wnt/β‐Catenin Signaling Pathway

Journal of Immunology Research, Volume 2026, Issue 1, 2026.
Aim of Study This study aimed to investigate the efficacy and mechanism of Chaiyin granules (CY) in improving acute lung injury (ALI) based on the gut–lung axis. Materials and Methods UHPLC‐ESI‐Q‐Exactive Orbitrap MS was used to analyze the active ingredients of CY. Establishment of lipopolysaccharide (LPS)–induced ALI mouse model and grouping: control,
Wenting Ni, He Xiao, Qun Feng, Shirong Li, Jingchun Yao, Guimin Zhang, Poorani Gurumallesh Prabu   +6 more
wiley   +1 more source

STUDY OF THE EFFECT OF THE SCUTELLARIA BAICALENSIS GEORGI EXTRACT ON THE CONTENT OF MINERALS IN THE BLOOD SERUM OF RATS UNDER "SOCIAL" STRESS

Siberian Journal of Life Sciences and Agriculture
Background. The study of the influence of "social" stress on biogenic elements involved in mineral metabolism and playing an important role in the life of the human body, the search for agents that have a leveling effect on their content, is an urgent ...
Valeria V. Uranova, Natalya A. Lomteva, Elena I. Kondratenko, Stepan V. Komarov   +3 more
doaj   +1 more source

Overexpression of Cinnamate 4-Hydroxylase and 4-Coumaroyl CoA Ligase Prompted Flavone Accumulation in Hairy Roots

Natural Product Communications, 2014
Scutellaria baicalensis Georgi, a species of the Lamiaceae family, is considered as one of the 50 fundamental herbs used in traditional Chinese medicine. In order to enhance flavone (baicalein, baicalin, and wogonin) content in S.
Young Seon Kim, Yeon Bok Kim, YeJi Kim, Mi Young Lee, Sang Un Park   +4 more
doaj   +1 more source

The effect of Scutellaria baicalensis Georgi on immune response in mouse model of experimental periodontitis

Journal of Dental Sciences, 2013
Background/purpose: A medicinal herb Scutellaria baicalensis Georgi has been reported to possess antibacterial and anti-inflammatory activities. In this study, the effect of aqueous extracts obtained from S.
Shiguang Huang, Qiling Huang, Bo Huang, Fangli Lu   +3 more
doaj   +1 more source

Chinese Herbal Medicines for Diabetic Cardio‐Cerebrovascular Diseases: Key Bioactive Metabolites and Action Mechanisms

Journal of Nutrition and Metabolism, Volume 2026, Issue 1, 2026.
Currently, the global incidence of diabetes is increasing, particularly in populous developing regions. In China, over 290 million people are affected by diabetic cardio‐cerebrovascular diseases. These diseases account for more than 40% of deaths and impose a significant economic burden on both society and families.
Ying Su, Shuwen Luo, Wei Li, Cuicui Cheng, Wei Liu, Xinyu Yang, Zhen Xing, Eric Gumpricht   +7 more
wiley   +1 more source

Organ-Specific Metabolic Shifts of Flavonoids in Scutellaria baicalensis at Different Growth and Development Stages

Molecules, 2018
Scutellaria baicalensis Georgi is a traditional Chinese herbal medicine mainly containing flavonoids that contribute to its bioactivities. In this study, the distributions and dynamic changes of flavonoid levels in various organs of S.
Jingyuan Xu, Yilan Yu, Ruoyun Shi, Guoyong Xie, Yan Zhu, Gang Wu, Minjian Qin   +6 more
doaj   +1 more source

Yiqi–Wenyang–Tiaoshen Decoction Reduces Cisplatin‐Induced Acute Kidney Injury in Rats Through Autophagy and Apoptosis Signaling Pathways Based on Network Pharmacology and Experimental Validation

Mediators of Inflammation, Volume 2026, Issue 1, 2026.
Context The mechanism of Yiqi–Wenyang–Tiaoshen decoction (YWT) in treating cisplatin‐induced acute kidney injury (AKI) remains unknown. Objective This study identifies the key components of YWT and explores its therapeutic potential and mechanisms in a cisplatin‐induced AKI rat model.
Yunqi Bai, Yue Chang, Lili Zhang, Wenjing Zhou, Yixin Su, Jingwei Zhou, Jingru Tian   +6 more
wiley   +1 more source

Getah Virus in Review: An Emerging Zoonotic Arbovirus

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Getah virus (GETV), a zoonotic virus, belongs to Togaviridae, Alphavirus. GETV leads to diarrhea in piglets and dysfunction of the reproductive system in sows, with pregnant sows potentially experiencing abortion, fetal death, or weak offspring, causing a severe impact on the livestock industry and resulting in economic losses.
Zhengyi Qiu, Duo Zhang, Qingmiao Fan, Zhihao Hu, Haobin Xie, Nan Li, Pengpeng Xiao, Shao-Lun Zhai   +7 more
wiley   +1 more source

Generation of Potential Therapeutic Lactobacillus Derived Exopolysaccharides as Functional Food Ingredients That May Aid in the Control of Chronic Inflammation and Inflammatory Bowel Disease

eFood, Volume 6, Issue 6, December 2025.
Exopolysaccharides (EPS) from Lactobacillus strains LB327, LKF13, and LRH28 were produced in MRS media and characterized by FTIR, revealing typical protein and carbohydrate peaks. In LPS‐stimulated in vitro murine models, EPS reduced IL‐1β and TNF‐α, increased IL‐10 and IL‐6, showing anti‐inflammatory potential for managing chronic inflammation ...
Dearbhla Finnegan, Helena Mylise Copeland, Brian Freeland, Christine Loscher   +3 more
wiley   +1 more source