Needle-scalpel therapy inhibits the apoptosis of nucleus pulposus cells via the SDF-1/CXCR4 axis in a rat degenerative cervical intervertebral disc model. [PDF]
Yang W +6 more
europepmc +1 more source
Transcriptomics and Proteomics Reveal That TLPW Acupuncture Ameliorates Proteinuria in Diabetic Kidney Disease Model Rats by Suppressing Epithelial-to-Mesenchymal Transition via the DPP4/SDF-1α/TGF-β/Smad Signalling Axis. [PDF]
Ji Y +7 more
europepmc +1 more source
Expression of Concern: Long Non-Coding RNA-H19 Stimulates Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells via the MicroRNA-149/SDF-1 Axis. [PDF]
europepmc +1 more source
Portulaca oleracea L seed extracts counteract diabetic nephropathy through SDF-1/IL10/PPARγ-mediated tuning of keap1/Nrf2 and NF-κB transcription in Sprague Dawley rats. [PDF]
Aziz WM +5 more
europepmc +1 more source
Overexpression of Nrf2 in bone marrow mesenchymal stem cells promotes B-cell acute lymphoblastic leukemia cells invasion and extramedullary organ infiltration through stimulation of the SDF-1/CXCR4 axis. [PDF]
Zheng L +11 more
europepmc +1 more source
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SDF-1 keeps HSC quiescent at home
Blood, 2011In this issue of Blood , Tzeng et al report on the generation of adult, conditional SDF-1–deficient mice in which HSC quiescence and endosteal niche localization are impaired.[1][1] The chemokine stromal cell–derived factor 1 (SDF-1; CXCL12), and its major receptor CXCR4, regulate many ...
Tomer, Itkin, Tsvee, Lapidot
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Functional Characterization of SDF-1 Proximal Promoter
Journal of Molecular Biology, 2005Stromal-cell derived factor 1 (SDF1) is a CXC chemokine that binds and signals through the CXCR4 receptor, playing an essential role in embryonic B lymphopoiesis, myelopoiesis and organogenesis. The CXCR4/SDF1 pathway is associated with several pathologies.
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