Results 51 to 60 of about 63,696 (276)
Quantitative Phosphoproteomics of CXCL12 (SDF-1) Signaling
PLoS ONE, 2011 CXCL12 (SDF-1) is a chemokine that binds to and signals through the seven transmembrane receptor CXCR4. The CXCL12/CXCR4 signaling axis has been implicated in both cancer metastases and human immunodeficiency virus type 1 (HIV-1) infection and a more complete understanding of CXCL12/CXCR4 signaling pathways may support efforts to develop therapeutics ...
Jason A Wojcechowskyj +3 more
openaire +4 more sources
MiR-9 Controls Chemotactic Activity of Cord Blood CD34⁺ Cells by Repressing CXCR4 Expression [PDF]
, 2018 Improved approaches for promoting umbilical cord blood (CB) hematopoietic stem cell (HSC) homing are clinically important to enhance engraftment of CB-HSCs. Clinical transplantation of CB-HSCs is used to treat a wide range of disorders.
Broxmeyer, Hal E. +11 more
core +1 more source
Journal of Materials Science: Materials in MedicineThis study investigated whether octacalcium phosphate (OCP) enhances bone regeneration through its synergistic effect with stromal-derived factor-1 (SDF-1). Recombinant SDF-1 (0.5–5.0 μg) was combined with OCP granules through lyophilization.
Ryuichi Kanabuchi +8 more
doaj +1 more source
SDF-1 directs megakaryocyte relocation
Blood, 2014 In this issue of Blood, Niswander et al answer the questions: (1) Does stromal cell-derived factor 1 (SDF-1) direct megakaryocyte spatial distribution in the bone marrow? and (2) What effect does local SDF-1 concentration have on platelet output?1 If Jose Arcadio Buendia in One Hundred Years of Solitude2 had followed SDF-1, as megakaryocytes do ...
openaire +3 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang +10 more
wiley +1 more source
Dentistry ReviewOBJECTIVES: Exo released by immune-regulatory dendritic cells (regDCs) have been used as an effective nanodelivery system for the reprogramming of immune response at inflammatory bone defects in mice.
Cathy Tran, Ranya Elsayed, PhD MBA
doaj +1 more source
CXCL12/SDF-1 facilitates optic nerve regeneration
Neurobiology of Disease, 2013 Mature retinal ganglion cells (RGCs) do not normally regenerate injured axons, but undergo apoptosis soon after axotomy. Besides the insufficient intrinsic capability of mature neurons to regrow axons inhibitory molecules located in myelin of the central nervous system as well as the glial scar forming at the site of injury strongly limit axon ...
Annemarie Heskamp +5 more
openaire +3 more sources
Advanced Functional Materials, EarlyView.Herein presented supraparticles combine the nanoparticulate photocatalyst graphitic carbon nitride with the enzyme horseradish peroxidase, which is immobilized on silica nanoparticles. In an optimized compatibility range, both catalysts operate effectively within the hybrid supraparticles and catalyze a cascade reaction consisting of the photocatalytic
Bettina Herbig +11 more
wiley +1 more source
Questions about Chemokine and Chemokine Receptor Antagonism in Renal Inflammation [PDF]
, 2010 Chemokines remain attractive therapeutic targets for modulating inflammatory diseases in all areas of medicine including acute and chronic kidney disease.
Anders, Hans-Joachim +2 more
core +1 more source
Advanced Functional Materials, EarlyView.Tumor‐tropic human mesenchymal stem cells (hMSCs) were used as delivery vehicles for magnetotheranostic gold–iron oxide nanoflowers. Magnetic particle imaging of the iron component demonstrated widespread intratumoral distribution and sustained retention in contrast to injection of naked nanoflowers.
Behnaz Ghaemi +7 more
wiley +1 more source