Results 11 to 20 of about 3,433 (163)

Secoisolariciresinol Diglucoside of Flaxseed and Its Metabolites: Biosynthesis and Potential for Nutraceuticals [PDF]

Frontiers in Genetics, 2018
Secoisolariciresinol diglucoside (SDG), found mainly in flaxseed, is one of the essential lignans. SDG, as well as the beneficial fatty acid composition and high fiber content, has made flaxseed an important source of functional food or nutraceutical ...
Parfait Kezimana, Parfait Kezimana, Alexey A. Dmitriev, Anna V. Kudryavtseva, Elena V. Romanova, Nataliya V. Melnikova   +5 more
doaj   +3 more sources

Structure, properties and obtention routes of flaxseed lignan secoisolariciresinol: a review [PDF]

Biotechnologie, Agronomie, Société et Environnement, 2012
Following a brief description of the structure and nomenclature of the lignan family, this review focuses on the flaxseed lignan secoisolariciresinol (SECO).
Sainvitu, P., Nott, K., Richard, G., Blecker, C., Jérôme, C., Wathelet, JP., Paquot, M., Deleu, M.   +7 more
doaj   +1 more source

Negative-Pressure Cavitation Extraction of Secoisolariciresinol Diglycoside from Flaxseed Cakes

Molecules, 2015
The negative-pressure cavitation extraction (NPCE) technique was applied firstly to extract secoisolariciresinol diglucoside (SDG) from flaxseed cakes. The significant extraction parameters were screened by fractional factorial design (FFD).
Hao Tian, Wan-Yi Li, Dan Xiao, Zhi-Min Li, Jian-Wen Wang   +4 more
doaj   +2 more sources

Water Stress and Seed Color Interacting to Impact Seed and Oil Yield, Protein, Mucilage, and Secoisolariciresinol Diglucoside Content in Cultivated Flax (Linum usitatissimum L.)

Plants, 2023
Flaxseed (Linum usitatissimum L.) is a plant with a wide range of medicinal, health, nutritional, and industrial uses. This study assessed the genetic potential of yellow and brown seeds in thirty F4 families under different water conditions concerning ...
Sara Zare, Aghafakhr Mirlohi, Mohammad R. Sabzalian, Ghodratollah Saeidi, Mehmet Zeki Koçak, Christophe Hano   +5 more
doaj   +2 more sources

Histidine 352 (His352) and tryptophan 355 (Trp355) are essential for flax UGT74S1 glucosylation activity toward secoisolariciresinol.

PLoS ONE, 2015
Flax secoisolariciresinol diglucoside (SDG) lignan is a natural phytoestrogen for which a positive role in metabolic diseases is emerging. Until recently however, much less was known about SDG and its monoglucoside (SMG) biosynthesis.
Kaushik Ghose, Jason McCallum, Marva Sweeney-Nixon, Bourlaye Fofana   +3 more
doaj   +2 more sources

Secoisolariciresinol Diglucoside Alleviates LPS-Induced Acute Lung Injury by Inhibiting the NF-κB/NLRP3 Signaling Pathway. [PDF]

Drug Dev Res
ABSTRACT Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS), are life‐threatening pulmonary disorders with high mortality rates, and effective treatments are currently lacking. Secoisolariciresinol diglucoside (SDG), a plant lignan derived from flaxseed, possesses anti‐inflammatory and antioxidative activities.
Zhong Y, Zou Y, Qu Z, Zhou K, Liu H, Yang J, Tang C, Xu Y, Wang Z.   +8 more
europepmc   +2 more sources

Importance of interaction between the matrix effect and microbial metabolism in the bioavailability of lignans. [PDF]

J Sci Food Agric
Abstract BACKGROUND Plant‐lignans are polyphenols with low bioavailability and bioactivity that are transformed by the intestinal microbiota into enterolignans. Our hypotheses are: (i) the way in which plant‐lignans are ingested in the diet affects, in a decisive way, the microbial metabolism of these compounds and (ii) an increase in lignan ...
Langa S, Curiel JA, de la Bastida R, Peirotén Á, Landete JM.   +4 more
europepmc   +2 more sources

Assessment of Liver and Kidney Safety of Silver Fir (<i>Abies alba</i>) Branch Extract: An Open-Label Human Study of a Dietary Supplement. [PDF]

Food Sci Nutr
This study evaluated the short‐term effects of a standardized silver fir (Abies alba) branch extract (SFBE, Belinal) on biochemical markers of liver and kidney function in healthy adults. No statistically significant or clinically meaningful changes in hepatic or renal biomarkers were observed after 14 days of supplementation with 900 mg/day SFBE ...
Schoss K, Kreft S.
europepmc   +2 more sources

Sample Preparation and Separation of Lignans by Liquid Chromatography. [PDF]

J Sep Sci
ABSTRACT Lignans are important phytochemicals found mostly in the resins of coniferous trees, but are also introduced into human diets through foods such as sesame seeds and extra‐virgin olive oil. They are pharmacologically interesting mainly because of their antioxidant activities, and they have also been shown to have cytotoxic and antimicrobial ...
Paloluoto M, Wiedmer SK.
europepmc   +2 more sources

Polyphenolic Components and Phytochemicals Deployed as Nutraceuticals and Pharmafoods. [PDF]

Food Sci Nutr
This review (2010–2025) highlights the therapeutic potential of dietary polyphenols against cancer, diabetes, cardiovascular, neurological, and inflammatory diseases. It summarizes molecular mechanisms, clinical evidence, nanoparticle‐based delivery, bioavailability, safety, toxicity, and future prospects supporting polyphenols as promising therapeutic
Chandra S, Al Hasan MS, Azad MAK, Goswami A.   +3 more
europepmc   +2 more sources