Results 21 to 30 of about 6,888,408 (247)

Cyclic di-GMP Signaling in Bacillus subtilis Is Governed by Direct Interactions of Diguanylate Cyclases and Cognate Receptors

open access: yesmBio, 2020
Bacillus subtilis contains two known cyclic di-GMP (c-di-GMP)-dependent receptors, YdaK and DgrA, as well as three diguanylate cyclases (DGCs): soluble DgcP and membrane-integral DgcK and DgcW.
Sandra Kunz   +5 more
doaj   +1 more source

Plasmodium falciparum cGMP-Dependent Protein Kinase – A Novel Chemotherapeutic Target

open access: yesFrontiers in Microbiology, 2021
The primary effector of cGMP signaling in Plasmodium is the cGMP-dependent protein kinase (PKG). Work in human-infective Plasmodium falciparum and rodent-infective Plasmodium berghei has provided biological validation of P.
David Rotella   +2 more
doaj   +1 more source

Emerging Trend In Second Messenger Communication And Myoendothelial Feedback

open access: yesFrontiers in Physiology, 2014
Over the past decade, second messenger communication has emerged as one of the intriguing topics in the field of vasomotor control. Of particular interest has been the idea of second messenger flux from smooth muscle to endothelium initiating a feedback
Cam Ha T. Tran   +2 more
doaj   +1 more source

Bicarbonate and Ca2+ sensing modulators activate photoreceptor ROS-GC1 synergistically

open access: yesFrontiers in Molecular Neuroscience, 2016
Photoreceptor ROS-GC1, a prototype subfamily member of the membrane guanylate cyclase family, is a central component of phototransduction. It is a single transmembrane-spanning protein, composed of modular blocks.
Teresa eDuda   +3 more
doaj   +1 more source

Neurotoxicity of a Novel Local Anesthetic Agent, Ropivacaine: The Possible Roles of Bursts of Potential and Cytoplasmic Second Messenger

open access: yesJournal of the Formosan Medical Association, 2007
Ropivacaine has been shown to induce convulsion following overdose or accidental intravenous injection, but the mechanisms are poorly understood.
Pei-Lin Lin   +5 more
doaj   +1 more source

25 Years of Collaboration with A Genius: Deciphering Adenine Nucleotide Ca2+ Mobilizing Second Messengers Together with Professor Barry Potter

open access: yesMolecules, 2020
Ca2+-mobilizing adenine nucleotide second messengers cyclic adenosine diphosphoribose, (cADPR), nicotinic acid adenine dinucleotide phosphate (NAADP), adenosine diphosphoribose (ADPR), and 2′deoxy-ADPR were discovered since the late 1980s.
Andreas H. Guse
doaj   +1 more source

Recent advances on the regulation of bacterial biofilm formation by herbal medicines

open access: yesFrontiers in Microbiology, 2022
Biofilm formation is a fundamental part of life cycles of bacteria which affects various aspects of bacterial-host interactions including the development of drug resistance and chronic infections.
Meimei Zhang   +9 more
doaj   +1 more source

Scents and sensibility: how biology perceives chemistry

open access: yesFrontiers in Integrative Neuroscience, 2014
The olfactory system plays a leading role in the perception of flavors, even though we experience this perception in our oral cavity as "taste". Without a sense of smell, food loses all but its most elementary flavor qualities.
Stuart Firestein
doaj   +1 more source

Locating the ‘radical’ in 'Shoot the Messenger' [PDF]

open access: yes, 2013
This is the author's accepted manuscript. The final published article is available from the link below, copyright 2013 @ Edinburgh University Press.The 2006 BBC drama Shoot the Messenger is based on the psychological journey of a Black schoolteacher, Joe
Malik, S
core   +1 more source

The virulence factor regulator and quorum sensing regulate the type I-F CRISPR-Cas mediated horizontal gene transfer in Pseudomonas aeruginosa

open access: yesFrontiers in Microbiology, 2022
Pseudomonas aeruginosa is capable of thriving in diverse environments due to its network of regulatory components for effective response to stress factors.
Stephen Dela Ahator   +5 more
doaj   +1 more source

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