Results 51 to 60 of about 360,391 (324)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

3-Econsystems: microRNAs, receptors, and latent viruses; some insights biology can gain from economic theory

open access: yesFrontiers in Microbiology, 2016
This mini-review describes three biological systems. All three include competing molecules and a limiting molecule that binds the competing molecules. Such systems are extensively researched by economists.
Hanan ePolansky, Adrian eJavaherian
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

The Response of Cupriavidus metallidurans CH34 to Cadmium Involves Inhibition of the Initiation of Biofilm Formation, Decrease in Intracellular c-di-GMP Levels, and a Novel Metal Regulated Phosphodiesterase

open access: yesFrontiers in Microbiology, 2019
Cadmium is a highly toxic heavy metal for biological systems. Cupriavidus metallidurans CH34 is a model strain to study heavy metal resistance and bioremediation as it is able to deal with high heavy metal concentrations. Biofilm formation by bacteria is
Pablo Alviz-Gazitua   +8 more
doaj   +1 more source

Instant messaging clients - Relaxed, free & enjoyable English learning and training tools [PDF]

open access: yes, 2007
In a demanding world of using English as a second language, computer technology and the internet are being dominantly used as they provide an incredible boost to language learning environment.
Abu Bakar, Hanif Suhairi   +1 more
core  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Survival Strategies in the Aquatic and Terrestrial World: The Impact of Second Messengers on Cyanobacterial Processes

open access: yesLife, 2014
Second messengers are intracellular substances regulated by specific external stimuli globally known as first messengers. Cells rely on second messengers to generate rapid responses to environmental changes and the importance of their roles is becoming ...
Marco Agostoni, Beronda L. Montgomery
doaj   +1 more source

Eastern Taranaki Basin field guide. [PDF]

open access: yes, 2006
Linking the onshore and offshore parts of Eastern Taranaki Basin: Insights to stratigraphic architecture, sedimentary facies, sequence stratigraphy, paleogeography and hydrocarbon exploration from the on land ...
Kamp, Peter J.J., Vonk, Adam J.
core   +1 more source

Wiener filter reloaded: fast signal reconstruction without preconditioning

open access: yes, 2017
We present a high performance solution to the Wiener filtering problem via a formulation that is dual to the recently developed messenger technique.
Lavaux, Guilhem   +2 more
core   +2 more sources

Interplay between RNA‐protein interactions and RNA structures in gene regulation

open access: yesFEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko   +2 more
wiley   +1 more source

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