Histiocytes: Multifaceted Regulators of Health and Disease
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley +1 more source
P-Selectin Inhibition and the Structure-Activity Relationship of Sea Cucumber-Derived Fucosylated Glycosaminoglycan Oligosaccharides. [PDF]
Li S +7 more
europepmc +1 more source
Soluble Endothelium-selectin (sE-selectin) in Critically III Patients
全身性炎症反応性症候群(SIRS)は侵襲に対する生体反応としてTNF-αなどの炎症性サイトカインにより引き起こされる.この中には,一過性で自然軽快に向かうSIRSと,重篤な感染症・組織障害を伴い多臓器障害(MOF)へと重症化するSIRSがあり,両者を早期に鑑別診断できれば重篤化を防ぐことができ臨床上の利点が大きい.E-selectinはセレクチンファミリーに属する単鎖糖蛋白で,血管内皮細胞に分布し内皮と好中球・単球等の接着に関与する細胞接着分子の一つであり,炎症性サイトカインにより誘導され ...
SUZUKI, Tadashi +4 more
core
The role of extracellular vesicles in cell–cell crosstalk in cardiotoxicity
Abstract figure legend Administration of a pharmacological agent can result in off‐target cardiotoxicity which can be driven by cell–cell crosstalk between healthy and dysfunctional cardiac cells. Extracellular vesicles (EVs) are lipid bilayer structures that can move biological cargo between cells, facilitating cell–cell crosstalk.
Gabriella Bachynskyj‐Bilas +5 more
wiley +1 more source
Plasma PF4 is a reliable biomarker of platelet reactivity and predictive of bleeding risk in DAPT patients undergoing cardiac surgery. [PDF]
de Bezieux JR +8 more
europepmc +1 more source
Pulsed electric field (PEF) processing qualitatively reshapes the phytochemical profile of red beet extracts, resulting in enhanced endothelial bioefficacy. Compared with conventional extraction, PEF‐treated extracts more effectively restore nitric oxide signaling, suppress endothelial inflammation, and normalize vascular structure in high‐fat diet ...
Eunju Jang +8 more
wiley +1 more source
P-Selectin and Platelet-Monocyte Interaction in Inflammation: Mechanisms, Hypothesis, and Open Questions. [PDF]
Fernandes MKC +5 more
europepmc +1 more source
Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon +5 more
wiley +1 more source
E-selectin-targeted microbubbles combined with ultrasound improves renoprotective effects of methylprednisolone on cisplatin-induced acute kidney injury in rats. [PDF]
Si R +7 more
europepmc +1 more source

