Results 191 to 200 of about 74,821 (300)

Retraction Note: Carbon nano-onion-mediated dual targeting of P-selectin and P-glycoprotein to overcome cancer drug resistance. [PDF]

Nat Commun
Wang H, Liang Y, Yin Y, Zhang J, Su W, White AM, Jiang B, Xu J, Zhang Y, Stewart S, Lu X, He X.   +11 more
europepmc   +1 more source

PRMT5/Sohlh2/Sirt1 Signaling Pathway in Vascular Endothelial Cells Modulates Lung Metastasis of Triple‐Negative Breast Cancer

Advanced Science, Volume 13, Issue 31, 4 June 2026.
The cover image shows that vascular endothelial cells play an important role in lung metastasis of TNBC. Endothelial Sohlh2 acts as a gatekeeper against TNBC lung metastasis by limiting endothelial activation and tumor cell passage. PRMT5 reduces Sohlh2 stability, weakening this protective barrier.
Ruihong Zhang, Fengqin Wang, Lanlan Liu, Qi Zhang, Xiaoning Huo, Yanhui Nan, Yanli Dong, Yunling Xiao, Jing Hao   +8 more
wiley   +1 more source

Biomarker-based clustering identifies distinct pulmonary function trajectories in early systemic sclerosis. [PDF]

Front Immunol
Uesugi-Uchida S, Asano Y, Endo H, Goto D, Jinnin M, Kawaguchi Y, Koike Y, Kuwana M, Tanaka S, Makino K, Matsushita T, Motegi SI, Sumida H, Ueda-Hayakawa I, Toyama T, Hasegawa M.   +15 more
europepmc   +1 more source

Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology

Advanced Science, Volume 13, Issue 33, 15 June 2026.
Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu, Fan Wei, Chi Woo Yoon, Qifa Zhou, Yingxiao Wang   +4 more
wiley   +1 more source

SARS-CoV-2 Omicron variant spike protein maintains the ability to bind and activate human platelets: Comparison with the wild-type. [PDF]

Sci Rep
Kusudo E, Kawamoto S, Matsumoto T, Egi M.   +3 more
europepmc   +1 more source

Reprogramming the Immune Landscape of Inflammatory Breast Cancer

Advanced Science, Volume 13, Issue 36, 29 June 2026.
Inflammatory breast cancer is the most lethal subtype of breast cancer and is characterized by an immunosuppressive tumor microenvironment (TME) driven by a complex network of immune cells and inflammatory cytokines, contributing to its aggressiveness and treatment challenges. Immune checkpoint inhibitors, either alone or in combination, show potential
Verena Martinez‐Rodriguez, Suguru Ogata, Xiaoping Wang, Naoto T. Ueno   +3 more
wiley   +1 more source

Vascular inflammation in neuropsychiatric long COVID. [PDF]

Brain Behav Immun Health
McAlpine LS, Shorer EF, Chiarella J, Nelson A, Veenhuis R, Azola A, Lee A, Pierce R, Farhadian S, Rubin LH, Spudich SS, Yale COVID Mind, IMPACT Study Groups.   +12 more
europepmc   +1 more source

A Cooperative Release of Mitochondrial DNA From Platelets and Neutrophils Drives an Interferon Signature in Systemic Sclerosis

Arthritis &Rheumatology, Volume 78, Issue 6, Page 1281-1293, June 2026.
Objective Mitochondria are organelles with a hypomethylated circular genome. Mitochondrial DNA (mtDNA) in the systemic circulation has been implicated in inflammation. This study investigates the role of circulating DNA in systemic sclerosis (SSc) and the cellular mechanisms governing its release.
Stavros Giaglis, André N. Tiaden, Simone Häner‐Massimi, Diego Kyburz, Cedric André, Anton Glück, Enrico Ferrero, Stuart Hawtin, Tobias Junt, Ulrich A. Walker   +9 more
wiley   +1 more source

Immune disparities in the TME of EBV+ and EBV- BL: role of reactive oxygen species generation pathways and platelet activation. [PDF]

Blood Adv
Siciliano MC, Bertolazzi G, Glaser S, Granai M, Lori C, Boccacci R, Yellapragada SV, Vannucchi M, Ferrara D, Dreval K, Marafioti T, Quintanilla-Martinez L, Fend F, Morin RD, Ott G, Tripodo C, Siebert R, Lazzi S, Mbulaiteye SM, Leoncini L, Bellan C.   +20 more
europepmc   +1 more source

New Insights Into the Role of Neutrophils in Lymphoma

Cancer Medicine, Volume 15, Issue 6, June 2026.
Tissue‐resident neutrophils challenge conventional paradigms by actively infiltrating normal lymphoid organs, predominantly localizing in interstitial compartments, a spatial distribution distinct from their classical vascular positioning. Neutrophils in lymphoid organs exhibit unique phenotypic and functional signatures, suggesting they play roles in ...
Ling Gu
wiley   +1 more source