Results 11 to 20 of about 24,758 (269)
Терапевтический архив, 2021 Inflammatory diseases of the pancreas can range from acute to acute recurrent and chronic pancreatitis. With the improvement of laboratory diagnostics in the 21st century, the mechanisms of the pro-inflammatory and anti-inflammatory role of tight ...
Vadim A. Akhmedov, Olga V. Gaus
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Targeting cancer-associated glycans as a therapeutic strategy in leukemia
All Life, 2022 Unlike cytotoxic chemotherapy, cancer immunotherapy offers targeted therapies that exploit the effector mechanisms of the immune system to combat cancer.
Ashraf Abdullah Saad
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Frontiers in Medicine, 2020 Selectins [endothelial (E), platelet (P), and leucocytes (L)] are a class of cell adhesion molecules, stimulated in response to inflammation. Pre-eclampsia is characterized by inflammation, and angiotensin II is pro-inflammatory.
Hiten D. Mistry +5 more
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Perinatal Inflammation: Could Partial Blocking of Cell Adhesion Molecule Function Be a Solution?
Children, 2021 In spite of the great advances made in recent years in prenatal and perinatal medicine, inflammation can still frequently result in injury to vital organs and often constitutes a major cause of morbidity.
Nikolaos Vrachnis +9 more
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MRI Contrast Agents in Glycobiology
Molecules, 2022 Molecular recognition involving glycoprotein-mediated interactions is ubiquitous in both normal and pathological natural processes. Therefore, visualization of these interactions and the extent of expression of the sugars is a challenge in medical ...
Carlos F. G. C. Geraldes, Joop A. Peters
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Targeting Selectins Mediated Biological Activities With Multivalent Probes
Frontiers in Chemistry, 2021 Selectins are type-I transmembrane glycoproteins that are ubiquitously expressed on activated platelets, endothelial cells, and leukocytes. They bind to cell surface glycoproteins and extracellular matrix ligands, regulate the rolling of leukocytes in ...
Deepak Ganesh +4 more
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Animal lectins as cell adhesion molecules [PDF]
, 1998 Protein-carbohydrate interaction is exploited in cell adhesion mechanisms besides the recognition of peptide motifs. The sugar code thus significantly contributes to the intriguing specificity of cellular selection of binding partners.
Kaltner, H., Stierstorfer, B.
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Role of endothelial cells in graft-versus-host disease
Frontiers in Immunology, 2022 To date, the only curative treatment for high-risk or refractory hematologic malignancies non-responsive to standard chemotherapy is allogeneic hematopoietic transplantation (allo-HCT).
Lotus Neidemire-Colley +10 more
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Endothelial dysfunction markers as a therapeutic target for Sildenafil treatment and effects on metabolic control in type 2 diabetes [PDF]
, 2015 Endothelial dysfunction (ED) plays a role in diabetic cardiovascular complications. Hyperglycemia increases cytockines involved in vascular inflammation.
Bertolini, Camilla +10 more
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The chronic myeloid leukemia stem cell: stemming the tide of persistence [PDF]
, 2017 Chronic myeloid leukaemia (CML) is caused by the acquisition of the tyrosine kinase BCR-ABL1 in a haemopoietic stem cell (HSC), transforming it into a leukaemic stem cell (LSC) that self-renews, proliferates and differentiates to give rise to a ...
Holyoake, Tessa L., Vetrie, David
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