Results 11 to 20 of about 2,027 (239)
Maternal, Fetal, and Placental Selectins in Women With Pre-eclampsia; Association With the Renin-Angiotensin-System [PDF]
Frontiers in Medicine, 2020 Selectins [endothelial (E), platelet (P), and leucocytes (L)] are a class of cell adhesion molecules, stimulated in response to inflammation. Pre-eclampsia is characterized by inflammation, and angiotensin II is pro-inflammatory.
Hiten D. Mistry +5 more
doaj +3 more sources
Lung-Derived Selectins Enhance Metastatic Behavior of Triple Negative Breast Cancer Cells
Biomedicines, 2021 The lung is one of the deadliest sites of breast cancer metastasis, particularly for triple negative breast cancer (TNBC). We have previously shown that the lung produces several soluble factors that may enhance the metastatic behavior of TNBC, including
Sami U. Khan +4 more
doaj +2 more sources
Predictive value of plasma sICAM-1 and sP-Selectins in the risk of death in patients with acute respiratory distress syndrome [PDF]
Journal of Medical BiochemistryBackground: To evaluate the predictive value of sICAM-1 and sP-Selectins in the risk of death in a prospective cohort of adult acute respiratory distress syndrome (ARDS). Methods: Adult ARDS patients were included.
Jing Pan +4 more
doaj +3 more sources
Selectins in cancer immunity [PDF]
Glycobiology, 2018 Selectins are vascular adhesion molecules that mediate physiological responses such as inflammation, immunity and hemostasis. During cancer progression, selectins promote various steps enabling the interactions between tumor cells and the blood constituents, including platelets, endothelial cells and leukocytes.
Borsig, Lubor; https://orcid.org/ +1 more
openaire +5 more sources
Interplay of integrins and selectins in metastasis
Molecular OncologyMetastasis is a hallmark of malignancy and poses a formidable challenge for oncologists. This complex process begins when the primary malignant cells start to proliferate unlimitedly.
Diana Maltseva +2 more
doaj +2 more sources
Targeting Selectins and Their Ligands in Cancer
Frontiers in Oncology, 2016 Aberrant glycosylation is a hallmark of cancer cells with increased evidence pointing to a role in tumor progression. In particular, aberrant sialylation of glycoproteins and glycolipids have been linked to increased immune cell evasion, drug evasion ...
Alessandro eNatoni +3 more
doaj +2 more sources
Selectins modify dendritic cells during atherosclerosis
Chronic Diseases and Translational Medicine, 2018 Dendritic cells (DCs) are professional antigen-presenting cells (APC) that facilitate the development and progression of atherosclerosis. However, DCs also function as novel “switches” between immune activation and immune tolerance and represent a ...
Zhi-Shuai Ye, Rong-Chong Huang
doaj +2 more sources
Potential roles of selectins in periodontal diseases and associated systemic diseases: Could they be targets for immunotherapy? [PDF]
, 2022 Periodontal diseases are predisposing factors to the development of many systemic disorders, which is often initiated via leukocyte infiltration and vascular inflammation. These diseases could significantly affect human health and quality of life. Hence,
Lee, Learn-Han +7 more
core +3 more sources
Journal of Innate Immunity, 2021 Expression of the extensively glycosylated Ebolavirus glycoprotein (EBOV-GP) induces physical alterations of surface molecules and plays a crucial role in viral pathogenicity.
Mostafa Jarahian +11 more
doaj +1 more source
Biomedicines, 2022 Antiphospholipid syndrome (APS) is a systemic autoimmune disorder characterized by thrombosis and/or obstetric complications in the presence of antiphospholipid antibodies (aPL).
Ula Štok +6 more
doaj +1 more source