Results 41 to 50 of about 2,027 (239)
The role of selectins in the first trimester pregnancy loss [PDF]
, 1970 Objective: There are no well-defined findings about reasons for first trimester abortion in some pregnancy cases. Selectins are cell adhesion proteins which are important for blastocyst implantation in the decidua.
Kose, Can +3 more
core +1 more source
Clinical and Applied Thrombosis/Hemostasis, 2022 Introduction The pathophysiology of pulmonary embolism (PE) represents complex, multifactorial processes involving blood cells, vascular endothelium, and the activation of inflammatory pathways.
Iman Darwish B.S. +8 more
doaj +1 more source
Susceptibility to Infection and Altered Hematopoiesis in Mice Deficient in Both P- and E-Selectins [PDF]
, 1996 We describe the phenotype of mice lacking both endothelial selectins after sequential ablation of the genes encoding P- and E-selectins. In contrast with the rather mild phenotypes observed in mice deficient in a single selectin gene, the doubly ...
Wagner, Denisa D +4 more
core +1 more source
Regulation of T Cell Trafficking by Enzymatic Synthesis of O-Glycans
Frontiers in Immunology, 2017 Selectins constitute a family of oligosaccharide binding proteins that play critical roles in regulating the trafficking of leukocytes. In T cells, L-selectin (CD62L) controls the capacity for naive and memory T cells to actively survey peripheral lymph ...
Samuel J. Hobbs +3 more
doaj +1 more source
BMC Genomics, 2022 Background P-selectin is a molecule participating in the inflammatory response through mediating cellular adhesion and essential for wound repair. However, studies regarding P-selectin in Bivalvia are rare. This study identified 90 P-selectin genes among
Yuanfeng Xu +4 more
doaj +1 more source
CD34 Is a Ligand for Vascular Selectins on Human Hematopoietic Stem/Progenitor Cells
, 2015 The cell surface glycoprotein CD34 is widely recognized as a marker of hematopoietic stem/progenitor cells (HSPCs), but its physiological role on HSPCs remains elusive. Although CD34 is well recognized for mediating homing of L-selectin+ naïve T cells to
Abu Samra, Dina Bashir Kamil
core +1 more source
Sepsis: emerging role of nitric oxide and selectins [PDF]
Clinics, 2006 Sepsis-a state of systemic bacterial infection-often leads to multiorgan failure and is associated with high mortality despite the recent advances achieved in intensive care treatment.
Abhijit Chandra +4 more
doaj +1 more source
E- and p-selectins are essential for repopulation of chronic myelogenous and chronic eosinophilic leukemias in a scid mouse xenograft model. [PDF]
PLoS ONE, 2013 In chronic myelogenous (CML) and chronic eosinophilic leukemia (CEL), neoplastic cells spread via the circulation into various extramedullary organs. As E- and P-selectin constitute the starting point for the leucocyte adhesion/invasion cascade, and CEL ...
Daniel Wicklein +5 more
doaj +1 more source
Selectins facilitate metastasis and the role of heparin in cancer [PDF]
, 2008 Metastatic disease is the primary cause of death for most cancer patients. Metastasis is facilitated by tumor cell interactions with the surrounding host cells.
Borsig, L
core +2 more sources
Soluble selectins and highly fucosylated ?1-antichymotrypsin in rheumatoid arthritis patients
Journal of Medical Science, 2015 Introduction. Fucosylation of acute phase proteins and serum soluble selectin levels is increased in rheumatoid arthritis (RA) patients and can influence leukocyte extravasation. Aim.
Anna Olewicz-Gawlik +2 more
doaj +1 more source