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Journal of Experimental Medicine, 1996 The roles of selectins in the pulmonary margination and emigration of neutrophils were investigated by using mice genetically deficient in both E- and P-selectins (E/P mutants) and/or by intravenous injections of fucoidin (inhibiting both L- and P ...
Joseph P Mizgerd +2 more
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Mechanisms That Regulate the Function of the Selectins and Their Ligands
Physiological Reviews, 1999 Vestweber, Dietmar, and James E. Blanks. Mechanisms That Regulate the Function of the Selectins and Their Ligands. Physiol. Rev. 79: 181–213, 1999.
Dietmar Vestweber
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Susceptibility to Infection and Altered Hematopoiesis in Mice Deficient in Both P- and E-Selectins
Cell, 1996 We describe the phenotype of mice lacking both endothelial selectins after sequential ablation of the genes encoding P- and E-selectins. In contrast with the rather mild phenotypes observed in mice deficient in a single selectin gene, the doubly ...
Paul S Frenette +2 more
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The selectins and their ligands
Current Opinion in Cell Biology, 1994The selectins are a family of carbohydrate-binding proteins, or lectins, that have stimulated tremendous interest because of their involvement in a wide array of interactions between leukocytes and endothelial cells. Highlights of recent progress include an extension of the list of instances of selectin participation in inflammatory diseases, further ...
S D, Rosen, C R, Bertozzi
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Cancers, 2019 Acute myeloid and lymphoblastic leukemia are poor prognosis hematologic malignancies, which disseminate from the bone marrow into the blood. Blast interactions with selectins expressed by vascular endothelium promote the development of drug resistance ...
Olivier Spertini, Spertini Olivier
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Current Opinion in Immunology, 1994
The selectins are three related receptors that initiate rolling of leukocytes on activated platelets or endothelium through Ca(2+)-dependent recognition of cell surface carbohydrates. Cell adhesion may be enhanced by a limited number of membrane glycoproteins that present high affinity carbohydrate ligands to specific selectins.
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The selectins are three related receptors that initiate rolling of leukocytes on activated platelets or endothelium through Ca(2+)-dependent recognition of cell surface carbohydrates. Cell adhesion may be enhanced by a limited number of membrane glycoproteins that present high affinity carbohydrate ligands to specific selectins.
openaire +2 more sources