Aminoglycoside-driven biosynthesis of selenium-deficient Selenoprotein P [PDF]
Scientific Reports, 2017 Selenoprotein biosynthesis relies on the co-translational insertion of selenocysteine in response to UGA codons. Aminoglycoside antibiotics interfere with ribosomal function and may cause codon misreading.
Kostja Renko +11 more
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Selenoprotein P Regulates Synaptic Zinc and Reduces Tau Phosphorylation [PDF]
Frontiers in Nutrition, 2021 Selenoprotein P (SELENOP1) is a selenium-rich antioxidant protein involved in extracellular transport of selenium (Se). SELENOP1 also has metal binding properties.
Arlene C. P. Kiyohara +7 more
doaj +4 more sources
Autoimmunity to selenoprotein P predicts breast cancer recurrence [PDF]
Redox Biology, 2022 Background: Low concentrations of serum selenium (Se) and its main transporter selenoprotein P (SELENOP) are associated with a poor prognosis following breast cancer diagnosis.
Kamil Demircan +11 more
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A positive effect of selenoprotein on mammary gland: Selenoprotein P stabilizes tight junctions by reducing cell death through inflammation mitigation in mice [PDF]
Redox BiologyLactational mastitis threatens maternal-infant health and animal husbandry efficiency, with traditional antibiotics limited by milk residues and bacterial resistance.
Mengran Zhu +5 more
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Serum Selenoprotein P level is not indicative of Insulin Resistance in Children and Adolescents with Type 1 Diabetes Mellitus: Single Center Experience [PDF]
Pediatric Sciences Journal, 2022 Background: Selenium has an anti-diabetic action as it an insulin-mimetic and antioxidant nutrient. Selenoprotein P (SeP) is an extracellular glycoprotein, that was linked to insulin resistance (IR).
Hend Mehawed Soliman +3 more
doaj +2 more sources
A randomized trial of selenium supplementation and risk of type-2 diabetes, as assessed by plasma adiponectin [PDF]
, 2012 Background: Evidence that selenium affects the risk of type-2 diabetes is conflicting, with observational studies and a few randomized trials showing both lower and higher risk linked to the level of selenium intake and status. We investigated the effect
Eliseo Guallar +6 more
core +18 more sources
Selenoprotein P concentrations and risk of progression from mild cognitive impairment to dementia [PDF]
Scientific Reports, 2023 There is a growing literature investigating the effects of selenium on the central nervous system and cognitive function. However, little is known about the role of selenoprotein P, the main selenium transporter, which can also have adverse biological ...
Marco Vinceti +8 more
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Selenoprotein P regulation by the glucocorticoid receptor [PDF]
BioMetals, 2009 Maintenance of the antioxidant activity of selenoproteins is one potential mechanism of the beneficial health effects of selenium. Selenoprotein P is the primary selenium distribution protein of the body as well as the major selenium containing protein in serum.
Colleen Rock, Philip J. Moos
openalex +4 more sources
Mìžnarodnij Endokrinologìčnij Žurnal, 2023 Background. The specific role and place of genetic factors in the development of chronic pancreatitis and hypothyroidism, which determine the activity of glutathione antioxidant protection, have not been clarified. They are interconnected with changes in
V.V. Ratsa +6 more
doaj +3 more sources
SEPP1 (selenoprotein P, plasma, 1) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2012 Review on SEPP1 (selenoprotein P, plasma, 1), with data on DNA, on the protein encoded, and where the gene is implicated.
Ewa Jabłońska +3 more
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