Results 11 to 20 of about 18,127 (245)

Selenoprotein P controls oxidative stress in cornea. [PDF]

PLoS ONE, 2010
The ocular surface is always attacked by oxidative stress, and cornea epithelial cells are supposed to have their own recovery system against oxidative stress.
Akihiro Higuchi, Kazuhiko Takahashi, Masaki Hirashima, Tetsuya Kawakita, Kazuo Tsubota   +4 more
doaj   +4 more sources

Increases in Hepatokine Selenoprotein P Levels Are Associated With Hepatic Hypoperfusion and Predict Adverse Prognosis in Patients With Heart Failure [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Although multiorgan networks are involved in the pathophysiology of heart failure (HF), interactions of the heart and the liver have not been fully understood.
Ryohei Takeishi, Tomofumi Misaka, Yasuhiro Ichijo, Shinji Ishibashi, Mitsuko Matsuda, Yukio Yamadera, Himika Ohara, Yukiko Sugawara, Yu Hotsuki, Koichiro Watanabe, Fumiya Anzai, Yu Sato, Takamasa Sato, Masayoshi Oikawa, Atsushi Kobayashi, Takayoshi Yamaki, Kazuhiko Nakazato, Akiomi Yoshihisa, Yasuchika Takeishi   +18 more
doaj   +2 more sources

The selenoprotein P/ApoER2 axis facilitates selenium accumulation in selenoprotein P-accepting cells and confers prolonged resistance to ferroptosis [PDF]

Redox Biology
The essential trace element selenium (Se) plays a significant role in redox homeostasis, while Se is very reactive and has a potent toxicity. Understanding the molecular machinery that supports Se metabolism is important for the both physiological and ...
Atsuya Ichikawa, Takashi Toyama, Hiroki Taguchi, Satoru Shiina, Hayato Takashima, Kazuaki Takahashi, Yasumitsu Ogra, Ayako Mizuno, Kotoko Arisawa, Yoshiro Saito   +9 more
doaj   +2 more sources

The Association of Plasma Selenium and Selenoprotein P Levels with Depression Severity and Anxiety Symptoms Among Medical Students in Latvia [PDF]

Medicina
Background and Objectives: Oxidative stress has been identified as a key process involved in different diseases, particularly depression. Selenium (Se) protects against oxidative stress, one of the pathogenic mechanisms involved in affective disorders ...
Zanda Birģele, Paula Marija Vimba, Anastasija Ševčenko, Andrejs Šķesters, Gunta Ancāne, Laura Valaine   +5 more
doaj   +2 more sources

Gender differences in plasma element concentrations and associations between selenoprotein P and iron metabolism in a community-based cohort study [PDF]

Scientific Reports
Essential trace elements, such as iron (Fe) and selenium (Se), play physiological roles in our body, whereas environmental toxic metals, such as arsenic (As), cadmium (Cd), and mercury (Hg), are known to be associated with various disease risks. However,
Yoshiro Saito, Misaki Shimizu, Mitsuharu Sato, An Masuda, Kotoko Arisawa, Keiko Taguchi, Takashi Toyama, Ikuko N. Motoike, Kengo Kinoshita, Seizo Koshiba, Masayuki Yamamoto, Toshinari Takamura   +11 more
doaj   +2 more sources

Selenoprotein P. Its Structure and Functions.

Journal of Health Science, 2000
Selenoprotein P (SeP : the "P" denotes its presence in plasma) is the major selenoprotein in plasma. All selenoproteins so far reported contain one atom of selenium (Se) as selenocysteine per molecule except SeP, which is thought to contain ten atoms of Se as selenocysteine per molecule. SeP contains 50% of the total Se in plasma.
Yoshiro Saito, Kazuhiko Takahashi
openalex   +3 more sources

Excessive copper impairs intrahepatocyte trafficking and secretion of selenoprotein P [PDF]

Nature Communications, 2023
Selenium homeostasis depends on hepatic biosynthesis of selenoprotein P (SELENOP) and SELENOP-mediated transport from the liver to e.g. the brain. In addition, the liver maintains copper homeostasis. Selenium and copper metabolism are inversely regulated,
Maria Schwarz, Caroline E. Meyer, Alina Löser, Kristina Lossow, Julian Hackler, Christiane Ott, Susanne Jäger, Isabelle Mohr, Ella A. Eklund, Angana A. H. Patel, Nadia Gul, Samantha Alvarez, Ilayda Altinonder, Clotilde Wiel, Maria Maares, Hajo Haase, Anetta Härtlova, Tilman Grune, Matthias B. Schulze, Tanja Schwerdtle, Uta Merle, Hans Zischka, Volkan I. Sayin, Lutz Schomburg, Anna P. Kipp   +24 more
doaj   +2 more sources

New-onset autoantibodies to selenoprotein P following severe burn injury [PDF]

Frontiers in Immunology
The liver-derived selenium (Se) transporter selenoprotein P (SELENOP) declines in critical illness as a negative acute phase reactant and has recently been identified as an autoantigen.
Tabael L. Turan, Holger J. Klein, Holger J. Klein, Theresia Reding Graf, Thilo Samson Chillon, Jan A. Plock, Jan A. Plock, Lutz Schomburg   +7 more
doaj   +2 more sources

Immune aging impairs muscle regeneration via macrophage-derived anti-oxidant selenoprotein P [PDF]

EMBO Reports
Muscle regeneration is impaired with aging, due to both intrinsic defects of muscle stem cells (MuSCs) and alterations of their niche. Here, we monitor the cells constituting the MuSC niche over time in young and old regenerating mouse muscle.
Dieu-Huong Hoang, Jessica Bouvière, Johanna Galvis, Pauline Moullé, Orane Mercier, Eugenia Migliavacca, Ananga Ghosh, Gaëtan Juban, Sophie Liot, Pascal Stuelsatz, Fabien Le Grand, Jérôme N Feige, Rémi Mounier, Bénédicte Chazaud   +13 more
doaj   +3 more sources

Investigation of The Placental Levels of Vascular Endothelial Growth Factor B and Selenoprotein P and Their Relation with Birth Weight in Patients with Pre-eclampsia: A Case-Control Study [PDF]

International Journal of Fertility and Sterility
Background: Pre-eclampsia is a serious medical condition characterised by high blood pressure and signs of organdamage that is associated with adverse pregnancy outcomes, including low birth weight.
Hadi Eslahi, Mohsen Saravani, Mansour Shahraki, Abolfazl Payandeh, Mahnaz Rezaei, Marzieh Ghasemi, Saeedeh Salimi, Mahjob Sargazi-Taghazi   +7 more
doaj   +2 more sources