Role of microRNA-7 and selenoprotein P in hepatocellular carcinoma
Tumor Biology, 2017 There is an obvious need to diagnose hepatocellular carcinoma using novel non-invasive and sensitive biomarkers. In this regard, the aim of this study was to evaluate and correlate both relative quantification of microRNA-7 using quantitative real time ...
Marwa Tarek +5 more
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Selenium-Binding Protein 1 Indicates Myocardial Stress and Risk for Adverse Outcome in Cardiac Surgery [PDF]
, 2019 Selenium-binding protein 1 (SELENBP1) is an intracellular protein that has been detected in the circulation in response to myocardial infarction. Hypoxia and cardiac surgery affect selenoprotein expression and selenium (Se) status.
Kühn, Eike C. +8 more
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Mercury and selenium binding biomolecules in terrestrial mammals (Cervus elaphus and Sus scrofa) from a mercury exposed area [PDF]
, 2017 Acknowledgements The authors are grateful to Junta de Comunidades de Castilla-La Mancha (PCC-05-004-2, PAI06-0094, PCI-08-0096, PEII09-0032-5329) and the Ministerio de Economía y Competitividad (CTQ2013-48411-P) for financial support. M.J.
Fariñas, N. Rodríguez +5 more
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Molecular mechanism of selenoprotein P synthesis
Biochimica et Biophysica Acta (BBA) - General Subjects, 2018 Selenoprotein synthesis requires the reinterpretation of a UGA stop codon as one that encodes selenocysteine (Sec), a process that requires a set of dedicated translation factors. Among the mammalian selenoproteins, Selenoprotein P (SELENOP) is unique as it contains a selenocysteine-rich domain that requires multiple Sec incorporation events.In this ...
Sumangala, Shetty, Paul R, Copeland
openaire +3 more sources
Poultry Science, 2022 : This study's objective was to investigate the effects of dietary Se (in the form of selenomethionine) on the antioxidant activity and selenoprotein gene expressions in layer breeder roosters.
Cheng Long +10 more
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Characterization of the aerosol produced by infrared femtosecond laser ablation of polyacrylamide gels for the sensitive inductively coupled plasma mass spectrometry detection of selenoproteins [PDF]
, 2009 A 2D high repetition rate femtosecondlaserablation strategy (2-mm wide lane) previously developed for the detection of selenoproteins in gel electrophoresis by inductively coupled plasma mass spectrometry was found to increase signal sensitivity by a ...
Alexis, Joël +7 more
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Selenoproteins regulate macrophage invasiveness and extracellular matrix-related gene expression
BMC Immunology, 2009 Background Selenium, a micronutrient whose deficiency in diet causes immune dysfunction and inflammatory disorders, is thought to exert its physiological effects mostly in the form of selenium-containing proteins (selenoproteins).
Gladyshev Vadim N +8 more
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Selenium in biology: Facts and medical perspectives [PDF]
, 2000 Several decades after the discovery of setenium as an essential trace element in vertebrates approximately 20 eukaryotic and more than 15 prokaryotic selenoproteins containing the 21(st) proteinogenic amino acid, selenocysteine, have been identified ...
Brigelius-Flohé, Regina +5 more
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Selenoprotein Metabolism and Function: Evidence for More than One Function for Selenoprotein P [PDF]
The Journal of Nutrition, 2003 Biological functions of selenium are exerted by selenoproteins that contain selenocysteine in their primary structure. Selenocysteine is synthesized and inserted into proteins cotranslationally by a complex process. Families of selenoproteins include the glutathione peroxidases, the iodothyronine deiodinases and the thioredoxin reductases.
Raymond F, Burk +2 more
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Evolution of selenoproteins in the metazoan
BMC Genomics, 2012 Background The selenocysteine (Sec) containing proteins, selenoproteins, are an important group of proteins present throughout all 3 kingdoms of life.
Jiang Liang, Ni Jiazuan, Liu Qiong
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