Impact of treatment planning target volumen (PTV) size on radiation induced diarrhoea following selenium supplementation in gynecologic radiation oncology - a subgroup analysis of a multicenter, phase III trial [PDF]
, 2013 Background: In a previous analysis (Int J Radiat Oncol Biol Phys 70:828-835,2010), we assessed whether an adjuvant supplementation with selenium (Se) improves Se status and reduces the radiation-induced side-effects of patients treated by adjuvant ...
Adamietz, Irenäus A. +14 more
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Associations and interactions between variants in selenoprotein genes, selenoprotein levels and the development of abdominal aortic aneurysm, peripheral arterial disease, and heart failure. [PDF]
PLoS ONE, 2018 BACKGROUND:Little is known on the role of selenoprotein genes in cardiovascular disease. This study examines the associations of the SEPP1, SELENOS, TXNRD1, TXNRD2, GPX4, and SOD2 polymorphisms and selenoprotein P (SeP) and thioredoxin concentrations ...
Ewa Strauss +3 more
doaj +1 more source
Selenocysteine, pyrrolysine and the unique energy metabolism of methanogenic archaea [PDF]
, 2010 Methanogenic archaea are a group of strictly anaerobic microorganisms characterized by their strict dependence on the process of methanogenesis for energy conservation.
Rother, Michael, Krzycki, Joseph A.
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A possible role for selenoprotein glutathione peroxidase (GPx1) and thioredoxin reductases (TrxR1) in thyroid cancer. Our experience in thyroid surgery [PDF]
, 2018 Background: Oxidative stress is responsible for some alterations in the chemical structure and, consequently, in the function of proteins, lipids, and DNA.
DE LUCA, Alessandro +6 more
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Systemic adipokines, hepatokines and interleukin-6 in HCV-monoinfected and HCV/HIV coinfected patients treated with direct antiviral agents (DAAs) [PDF]
, 2018 In this study, we demonstrated that that altered levels ofadipokines/hepatokines in HCV-infected patients, including HIV coinfected, can be restored by treatment with direct antiviral agents (DAAs), thus indicating the important metabolic changes ...
Alfieri, Giulia +10 more
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Germline genetic variation in prostate susceptibility does not predict outcomes in the chemoprevention trials PCPT and SELECT [PDF]
, 2020 Background The development of prostate cancer can be influenced by genetic and environmental factors. Numerous germline SNPs influence prostate cancer susceptibility.
Ahmed, M +7 more
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Altered hippocampus synaptic function in selenoprotein P deficient mice
Molecular Neurodegeneration, 2006 Selenium is an essential micronutrient that function through selenoproteins. Selenium deficiency results in lower concentrations of selenium and selenoproteins.
Peters Melinda M +3 more
doaj +1 more source
Selenium supplementation for the primary prevention of cardiovascular disease [PDF]
, 2013 Background: Selenium is a key component of a number of selenoproteins which protect against oxidative stress and have the potential to prevent chronic diseases including cardiovascular disease (CVD).
Clarke, Aileen +5 more
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Selenium and selenoprotein P1 levels are related to primary open-angle glaucoma [PDF]
Journal of Medical Biochemistry, 2014 Background: Glaucoma is a highly prevalent eye disease related to optic nerve lesions and visual field defects. Primary Open-Angle Glaucoma (POAG) is a type of glaucoma that occurs frequently with unknown etiology.
Najafi Mohammad +4 more
doaj
Friend or foe? The current epidemiologic evidence on selenium and human cancer risk. [PDF]
, 2013 Scientific opinion on the relationship between selenium and the risk of cancer has undergone radical change over the years, with selenium first viewed as a possible carcinogen in the 1940s then as a possible cancer preventive agent in the 1960s-2000s ...
Ammar E M +48 more
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