Results 11 to 20 of about 14,594 (219)
Monitoring genomic sequences during SELEX using high-throughput sequencing: neutral SELEX. [PDF]
PLoS ONE, 2010 BACKGROUND: SELEX is a well established in vitro selection tool to analyze the structure of ligand-binding nucleic acid sequences called aptamers. Genomic SELEX transforms SELEX into a tool to discover novel, genomically encoded RNA or DNA sequences ...
Bob Zimmermann +4 more
doaj +6 more sources
RAPID-SELEX for RNA aptamers. [PDF]
PLoS ONE, 2013 Aptamers are high-affinity ligands selected from DNA or RNA libraries via SELEX, a repetitive in vitro process of sequential selection and amplification steps.
Kylan Szeto +7 more
doaj +5 more sources
The Potential Use of Aptamers in The Process of Drug Development [PDF]
Pharmaceutical Sciences, 2021 Single-stranded nucleic acids can fold and create unique 3-dimensional structures when interacting with other molecules. The unique structure can achieve high specificity and affinity for the particular target.
Tooba Gholikhani +3 more
doaj +1 more source
Acta Biomedica Scientifica, 2022 Background. Aptamers are small single-stranded DNA or RNA molecules that have an affinity for a specific target molecule. The main method of aptamers construction is the technology of systematic evolution of ligands with exponential enrichment (SELEX ...
I. S. Solovarov +4 more
doaj +1 more source
Frontiers in Bioscience-Landmark, 2022 Background: Diazinon is a widely used organophosphorus neurotoxic insecticide. It is a common environmental contaminant and a hazardous agri-waste. Its detection is critical to control entry into food systems and protect the environment. Methods: In this
Mai-Huong Thi Can +11 more
doaj +1 more source
CyTA - Journal of Food, 2021 Deoxynivalenol (DON) is a mycotoxin commonly found in cereals and animal feeds, which also is a carcinogen easily soluble in water. So it has drawn considerable interest in food safety.
Mingwei Qin +6 more
doaj +1 more source
Imaging the coupling of terahertz radiation to a high electron mobility transistor in the near-field [PDF]
Journal of the European Optical Society-Rapid Publications, 2009 We used AlGaN/GaN high electron mobility transistors as room-temperature direct detectors of radiation at 0.15 THz from a free electron laser, hence 5 times higher than their cutoff frequency of 30 GHz.
Ortolani M. +12 more
doaj +1 more source
Aptamers and antibodies: rivals or allies in cancer targeted therapy?
Exploration of Targeted Anti-tumor Therapy, 2021 The goal of an efficacious cancer therapy is to specifically target diseased cells at high accuracy while sparing normal, healthy cells. Over the past three decades, immunotherapy, based on the use of monoclonal antibodies (mAbs) directed against tumor ...
Lisa Agnello +3 more
doaj +1 more source
Evolution of Multivalent Aptamer Corona for High-Throughput Multiplexed Detection of Multiple Cancers. [PDF]
Adv Sci (Weinh)A multivalent aptamer corona is evolved via established ProteoFish‐SELEX (systematic evolution of ligands by exponential enrichment) for high‐throughput multiplexed detection of multiple cancers. Clinical validation using multivalent aptamer corona demonstrated high accuracy and specificity in multiplexed detection of ovarian, lung, and colorectal ...
Wang M +10 more
europepmc +2 more sources
Recent results from selex [PDF]
Nuclear Physics B - Proceedings Supplements, 2001 Preliminary results on asymmetry for Lc produced by Sigma-,pi- and p beams at xf>0.2 and precise measurements of the Lc,D0 and Ds lifetimes are presented.
SELEX Collaboration, Iori, M.
openaire +4 more sources