Results 11 to 20 of about 22,058 (247)
Monitoring genomic sequences during SELEX using high-throughput sequencing: neutral SELEX. [PDF]
PLoS ONE, 2010 BACKGROUND: SELEX is a well established in vitro selection tool to analyze the structure of ligand-binding nucleic acid sequences called aptamers. Genomic SELEX transforms SELEX into a tool to discover novel, genomically encoded RNA or DNA sequences ...
Bob Zimmermann +4 more
doaj +6 more sources
AIP Conference Proceedings, 2000 A summary of the path which lead to a high energy physics group at Instituto de Fisica de la Universidad Autonoma de San Luis Potosi is presented. This group is the result of the initial push made by Leon Lederman at the beginning of the 80's.Comment ...
Morelos, A.
core +2 more sources
RAPID-SELEX for RNA aptamers. [PDF]
PLoS ONE, 2013 Aptamers are high-affinity ligands selected from DNA or RNA libraries via SELEX, a repetitive in vitro process of sequential selection and amplification steps.
Kylan Szeto +7 more
doaj +5 more sources
Performing SELEX experiments in silico [PDF]
The Journal of Chemical Physics, 2017 Due to the sequence-dependent nature of the elasticity of DNA, many protein-DNA complexes and other systems in which DNA molecules must be deformed have preferences for the type of DNA sequence they interact with. SELEX (Systematic Evolution of Ligands by EXponential enrichment) experiments and similar sequence selection experiments have been used ...
Joeri A. J. Wondergem +2 more
openalex +5 more sources
Enriching Higher Affinity Aptamers by Addressing the Kinetic Aspect of the DNA Strand-Displacement Reaction. [PDF]
Angew Chem Int Ed EnglCapture‐SELEX for ampicillin aptamers led to the dominance of a low‐affinity aptamer, while extending the target‐library incubation time significantly increased the abundance of a high‐affinity aptamer, revealing a previously unrecognized kinetic effect in the DNA strand displacement reaction during SELEX.
Ding Y, Heng Y, Wong KY, Chen Q, Liu J.
europepmc +3 more sources
Imaging the coupling of terahertz radiation to a high electron mobility transistor in the near-field [PDF]
Journal of the European Optical Society-Rapid Publications, 2009 We used AlGaN/GaN high electron mobility transistors as room-temperature direct detectors of radiation at 0.15 THz from a free electron laser, hence 5 times higher than their cutoff frequency of 30 GHz.
Ortolani M. +12 more
doaj +1 more source
Recent results from selex [PDF]
Nuclear Physics B - Proceedings Supplements, 2001 Preliminary results on asymmetry for Lc produced by Sigma-,pi- and p beams at xf>0.2 and precise measurements of the Lc,D0 and Ds lifetimes are presented.
SELEX Collaboration, Iori, M.
openaire +4 more sources
Aptamers and antibodies: rivals or allies in cancer targeted therapy?
Exploration of Targeted Anti-tumor Therapy, 2021 The goal of an efficacious cancer therapy is to specifically target diseased cells at high accuracy while sparing normal, healthy cells. Over the past three decades, immunotherapy, based on the use of monoclonal antibodies (mAbs) directed against tumor ...
Lisa Agnello +3 more
doaj +1 more source
Measuring the masses of the charged hadrons using a RICH as a precision velocity spectrometer [PDF]
, 2010 The Selex experiment measured several billion charged hadron tracks with a high precision magnetic momentum spectrometer and high precision RICH velocity spectrometer. We have analyzed these data to simultaneously measure the masses of all the long lived
Cooper, Peter S., Engelfried, Jurgen
core +2 more sources