Results 71 to 80 of about 22,058 (247)

Tri‐Layer Solid‐State Nanopore Arrays with Crosstalk Suppression for High‐Throughput, Femtomolar‐Level Biosensing

open access: yesAdvanced Science, EarlyView.
The critical pore spacing—approximately twenty times the pore radius—required to minimize electric field coupling is determined via finite element analysis. A multi‐layered Al2O3/Au/Si3N4 nanopore structure fabricated by helium ion beam lithography is proposed, enabling quantitative analysis of the target analyte while mitigating inter‐pore crosstalk ...
Silu Feng   +5 more
wiley   +1 more source

Tuning Polyacrylate Composition to Recognize and Modulate Fluorescent Proteins

open access: yesAngewandte Chemie, Volume 138, Issue 2, 9 January 2026.
Random hetero oligomers (RHOs) of defined compositions are synthesized and fractionated to identify the chemical design criteria (charge, length, hydrophobicity) required to achieve nanomolar binding to green fluorescent protein, resulting in >100% fluorescence increases.
Darwin C. Gomez   +12 more
wiley   +2 more sources

Plasma Proteomics Identifies TAOK3 as a Potential Biomarker of Rheumatoid Arthritis Activity and a Novel Therapeutic Target

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Bone destruction associated with active rheumatoid arthritis (RA) remains a major therapeutic challenge, with a lack of reliable molecular markers reflecting bone injury. This study aims to identify novel biomarkers linked to bone destruction in active RA through proteomic analysis, providing new strategies for precise monitoring and targeted
Pengfei Xin   +15 more
wiley   +1 more source

Is $D^{+}_{sJ}(2632)$ the first radial excitation of $D_{s}^{*}(2112)$?

open access: yes, 2005
We present a quantitative analysis of the $D^{+}_{sJ}(2632)$ observed by SELEX mainly focusing on the assumption that $D^{+}_{sJ}(2632)$ is the first radial excitation of the $1^{-}$ ground state $D^{*}_{s}(2112)$.
Barnes   +27 more
core   +1 more source

Mini‐Hairpin DNA: Extraordinarily Stable Structure and Its Applications

open access: yesChemistry – A European Journal, EarlyView.
Mini‐hairpin DNA fragments containing GCGAAGC and GCGAAAGC form exceptionally stable hairpin‐like structures, with only two G−C pairs and one sheared G−A pair, remaining undenatured in 7 M urea and resisting nuclease digestion. These mini‐hairpin sequences frequently appear in replication and transcription origins, influence DNA sequencing fidelity ...
Michiko Kimoto, Ichiro Hirao
wiley   +1 more source

Reliability Investigation of GaN HEMTs for MMICs Applications

open access: yesMicromachines, 2014
Results obtained during the evaluation of radio frequency (RF) reliability carried out on several devices fabricated with different epi-structure and field-plate geometries will be presented and discussed.
Alessandro Chini   +4 more
doaj   +1 more source

The Visible and Near Infrared module of EChO

open access: yes, 2014
The Visible and Near Infrared (VNIR) is one of the modules of EChO, the Exoplanets Characterization Observatory proposed to ESA for an M-class mission. EChO is aimed to observe planets while transiting by their suns.
Adriani, A.   +13 more
core   +1 more source

Rational Design Strategies for Stimuli‐Responsive DNAzymes Using Modified and Artificial Nucleotides

open access: yesChemistry – A European Journal, EarlyView.
Activity control of RNA‐cleaving DNAzymes in response to external stimuli has attracted growing interest for applications in DNA‐based diagnostics, therapeutics, and dynamic DNA nanotechnology. This review summarizes rational design strategies for stimuli‐responsive DNAzymes using modified or artificial nucleotides, including split and caged DNAzymes ...
Yusuke Takezawa, Mitsuhiko Shionoya
wiley   +1 more source

Judicial Review: Substance and Procedure

open access: yesThe Modern Law Review, EarlyView.
In this article we distinguish two questions about judicial review. First, substance: what acts or decisions are properly subject to the grounds of review? Second, procedure: what acts or decisions are properly reviewable through the judicial review procedure? Then we settle both.
Adam Perry, Angelo Ryu
wiley   +1 more source

Aptamer-based Theranostics in Oncology: Design Strategies and Limitations

open access: yesBIO Integration
Cancer remains a major global health burden, necessitating innovative approaches for improved diagnosis and treatment. Aptamer-based theranostics have gained attention in the field of cancer research and treatment.
Jyoti Trivedi   +3 more
doaj   +1 more source

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