Results 91 to 100 of about 2,506 (164)

Sema3C preserves type 2 alveolar epithelial cells (AEC2) viability in hyperoxia and promotes wound healing in vitro.

open access: yes, 2013
A. AEC2 were cultured for 48 hrs in room air (normoxic control) or 95% hyperoxia. Mean data of cell viability as assessed by measuring the mitochondrial-dependent reduction of colorless 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT ...
Arul Vadivel (424484)   +6 more
core   +1 more source

Role of Semaphorins in Angiogenesis and Innervation in Human Intervertebral Disc Degeneration

open access: yesGlobal Spine Journal, 2014
Introduction Although the intervertebral disc (IVD) is considered the largest aneural structure within the human body, during degeneration nociceptive nerves are seen to accompany blood vessels into the IVD yet it remains unclear how this process occurs.
A. LA. Binch   +7 more
doaj   +1 more source

The function of the retina is not compromised after a single bolus intravitreal injection of FR-sema3C.

open access: yes, 2016
(A) Six mice were injected with 2 μL of vehicle (100 mM glycine, 24 mM Tris, pH-7.2) in their right eyes and with 2 μl of FR-sema3C/Fc (0.1 μg) in their left eyes.
Shira Toledano (3609302)   +7 more
core   +1 more source

Localization of CR, Sema3C, and Npn1 in the coronal brain sections of WT and PlexinA1 KO mice at E17.5.

open access: yes, 2019
(A) Immunohistochemistry revealed the expression of Sema3C (arrows in b and e) in the CR-positive cells (arrows in a and d) in the cortical midline of brains of WT and PlexinA1 KO mice at E17.5.
Fumitaka Imaizumi (7288796)   +11 more
core   +1 more source

Roles of Sema3C on Breast Cancer Angiogenesis and Metastasis [PDF]

open access: yes, 2012
神经系统的发育依赖于一系列导向系统的控制。近年来的研究结果表明,神经导向系统不仅调控神经系统的发育,在血管新生和肿瘤发展等方面也发挥着重要的调控作用。神经生长导向因子Class3semaphorins(Sema3s)是脊椎动物中semaphorin家族中唯一一个的分泌型亚族。在Sema3s家族中的大部分成员在肿瘤发展过程中起抑制作用,而Sema3C却可能是一个促进肿瘤发展的因子。目前对于Sema3C在肿瘤中的作用主要集中在对肿瘤迁移、侵袭的影响等方面,对于肿瘤血管新生的影响还未见报道 ...
叶丽颖
core  

Correlation of peritumoral edema and microvessel density with tissue expression of VEGF, semaphorins 3A and 3C in patients with meningioma

open access: yesAsian Pacific Journal of Cancer Biology, 2019
Background: Several angiogenic factors correlate with angiogenesis in meningioma while their exact role is yet to be identified. Semaphorins are described with a variety of physiological functions including angiogenesis and migration of neural crest ...
Mahboobeh Razmkhah
doaj  

A genome-wide association study on hematopoietic stem cell transplantation reveals novel genomic loci associated with transplant outcomes

open access: yesFrontiers in Immunology
IntroductionData on genomic susceptibility for adverse outcomes after hematopoietic stem cell transplantation (HSCT) for recipients are scarce.MethodsWe performed a genome wide association study (GWAS) to identify genes associated with survival/mortality,
Albert Rosenberger   +8 more
doaj   +1 more source

Sema3C promotes pulmonary microvascular endothelial cells (PMVECs) network formation in hyperoxia.

open access: yes, 2013
A. PMVECs were cultured on matrigel in room air and in hyperoxia. PMVECs form cord-like structures within hours. Hyperoxia significantly decreases the aptitude of PMVECs to form vascular networks. B. C.
Arul Vadivel (424484)   +6 more
core   +1 more source

Implication of SEMA3C-induced steroidogenesis in the progression of castration-resistant prostate cancer

open access: yes, 2020
Androgens i.e. testosterone (T) and dihydrotestosterone (DHT), have essential roles in the differentiation and growth of normal prostate cells, as well as in the progression of prostate cancer (PCa) cells.
Yenki, Parvin
core  

Semaphorins: Novel Insights on Their Emerging Multifaceted Roles in the Evolving Landscape of Breast Cancer

open access: yesActa Medica Bulgarica
Semaphorins, initially identified as phylogenetically conserved axon guidance molecules, comprise an extracellular signaling protein family involved in various biological events that regulate the development, tissue homeostasis and cancer progression of ...
Popov Ts.
doaj   +1 more source

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