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Abstract 2525: Sema3C promotes glioma stem cell survival and radioresistance
Cancer Research, 2016Abstract Introduction: Different cancer cell compartments often communicate through soluble factors to facilitate tumor growth. Glioma stem cells (GSCs) are a subset of tumor cells that resist standard therapy to contribute to disease progression.
Jianghong Man +3 more
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The Role of Sema3c protein in vitro angiogenesis
2017Background and Aim: Angiogenesis is one of the key processes in the growth and development of tumor. Class 3 semaphorins (Sema3) are characterized as Nrp/plexin-mediated axon guidance factors involved in tumor angiogenesis by interacting with the VEGF signaling pathway.
Valiulytė, Indrė +5 more
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Flow Cytometry for Anti-SEMA3C [IPI-mSEM3C.5]
Experimental results for Anti-SEMA3C [IPI-mSEM3C.5] (Addgene #254647) in a flow cytometry assay with ExpiCHO cells expressing human or mouse SEMA3C.openaire +2 more sources
Development, 2012
The wiring of neuronal circuits requires complex mechanisms to guide axon subsets to their specific target with high precision. To overcome the limited number of guidance cues, modulation of axon responsiveness is crucial for specifying accurate trajectories.
Sanyas, Isabelle +3 more
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The wiring of neuronal circuits requires complex mechanisms to guide axon subsets to their specific target with high precision. To overcome the limited number of guidance cues, modulation of axon responsiveness is crucial for specifying accurate trajectories.
Sanyas, Isabelle +3 more
openaire +3 more sources
Sema3C signaling confers resistance to Wnt inhibition in glioblastoma
WFNOS 2022 Abstract Book, 2022Jennifer Yu +6 more
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Studies on Sema3C function in gliomagenesis
2019Secreted class 3 semaphorin (Sema3) proteins are involved in the regulation of cancer angiogenesis by interacting with components of the vascular endothelial growth factor (VEGF) signaling pathway. The relationships between the expression levels of individual semaphorins and their effectors and patient survival were determined in various cancer types ...
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ICC/IF for Anti-SEMA3C [IPI-mSEM3C.5] in binding assay
Experimental results for Anti-SEMA3C [IPI-mSEM3C.5] (Addgene #254647) in an immunofluorescence (IF) binding assay with ExpiCHO cells expressing human or mouse SEMA3C.openaire +2 more sources
An in vitro study of Sema3C effects on microcapillary formation and cell motility
2018Introduction. Angiogenesis is one of the main processes in the development of tumor, Class 3 semaphorins (Sema3) are characterized as axon guidance factors involved in tumor angiogenesis by interacting with the VEGF signaling pathways. Sema3 proteins convey their regulatory signals by binding to receptors neuropilins and plexins, which are located on ...
Valiulytė, Indrė +4 more
openaire +1 more source
Oncogene
The lack of effective, targeted therapies for gastric cancer (GC) continues to limit patient survival. Circular RNAs (circRNAs), known to act as epigenetic regulators, may also encode functional proteins. In this study, RNA-seq combined with ribosome profiling (Ribo-seq) of human GC cells identified a non-canonically translated circRNA, circSEMA3C ...
Siyu Xiao +17 more
openaire +2 more sources
The lack of effective, targeted therapies for gastric cancer (GC) continues to limit patient survival. Circular RNAs (circRNAs), known to act as epigenetic regulators, may also encode functional proteins. In this study, RNA-seq combined with ribosome profiling (Ribo-seq) of human GC cells identified a non-canonically translated circRNA, circSEMA3C ...
Siyu Xiao +17 more
openaire +2 more sources
ICC/IF for Anti-SEMA3C [IPI-mSEM3C.5] in specificity assay
Experimental results for Anti-SEMA3C [IPI-mSEM3C.5] (Addgene #254647) in an immunofluorescence (IF) specificity assay with ExpiCHO cells expressing human or mouse SEMA3s.openaire +1 more source

