Results 151 to 160 of about 2,506 (164)

The Role of Sema3c protein in vitro angiogenesis

2017
Background and Aim: Angiogenesis is one of the key processes in the growth and development of tumor. Class 3 semaphorins (Sema3) are characterized as Nrp/plexin-mediated axon guidance factors involved in tumor angiogenesis by interacting with the VEGF signaling pathway.
Valiulytė, Indrė, Preitakaitė, Viktorija, Steponaitis, Giedrius, Marčiulionytė, A., Tamašauskas, Arimantas, Kazlauskas, Arūnas   +5 more
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ICC/IF for Anti-SEMA3C [IPI-mSEM3C.5] in binding assay

Experimental results for Anti-SEMA3C [IPI-mSEM3C.5] (Addgene #254647) in an immunofluorescence (IF) binding assay with ExpiCHO cells expressing human or mouse SEMA3C.
openaire   +2 more sources

Studies on Sema3C function in gliomagenesis

2019
Secreted class 3 semaphorin (Sema3) proteins are involved in the regulation of cancer angiogenesis by interacting with components of the vascular endothelial growth factor (VEGF) signaling pathway. The relationships between the expression levels of individual semaphorins and their effectors and patient survival were determined in various cancer types ...
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Sema3C signaling confers resistance to Wnt inhibition in glioblastoma

WFNOS 2022 Abstract Book, 2022
Jennifer Yu, Jing Hao, Xiangzi Han, Haidong Huang, Xingjiang Yu, Richard Prayson, Shideng Bao   +6 more
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The novel protein SEMA3C-319aa triggers glutathione metabolism-dependent ferroptosis in gastric cancer

Oncogene
The lack of effective, targeted therapies for gastric cancer (GC) continues to limit patient survival. Circular RNAs (circRNAs), known to act as epigenetic regulators, may also encode functional proteins. In this study, RNA-seq combined with ribosome profiling (Ribo-seq) of human GC cells identified a non-canonically translated circRNA, circSEMA3C ...
Siyu Xiao, Yin Peng, Lehua Peng, Xiaoya Xie, Jiequan Qin, Huizhen Ma, Xinyi Kang, Chuhan Bing, Bingyan Huang, Ke Liang, Yidan Zhao, Xueying Rong, Xianling Feng, Xinmin Fan, Hassan Ashktorab, Zhong Zhang, Zhe Jin, Xiaojing Zhang   +17 more
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An in vitro study of Sema3C effects on microcapillary formation and cell motility

2018
Introduction. Angiogenesis is one of the main processes in the development of tumor, Class 3 semaphorins (Sema3) are characterized as axon guidance factors involved in tumor angiogenesis by interacting with the VEGF signaling pathways. Sema3 proteins convey their regulatory signals by binding to receptors neuropilins and plexins, which are located on ...
Valiulytė, Indrė, Kazlauskas, Arūnas, Preitakaitė, Viktorija, Steponaitis, Giedrius, Marčiulionytė, Aušra   +4 more
openaire   +1 more source

ICC/IF for Anti-SEMA3C [IPI-mSEM3C.5] in specificity assay

Experimental results for Anti-SEMA3C [IPI-mSEM3C.5] (Addgene #254647) in an immunofluorescence (IF) specificity assay with ExpiCHO cells expressing human or mouse SEMA3s.
openaire   +1 more source

The Role of Sema3C and R745A mutant on cell motility and microcapillary formation

2018
Introduction: Class 3 semaphorins (Sema3) are characterized as axon guidance factors involved in tumor angiogenesis by interacting with the VEGF signaling pathway. Sema3 proteins convey their regulatory signals by binding to receptors neuropilins and plexins, which are located on the effector cell.
Valiulytė, Indrė, Preitakaitė, Viktorija, Steponaitis, Giedrius, Kazlauskas, Arūnas   +3 more
openaire   +1 more source

Implication of SEMA3C-induced steroidogenesis in the progression of castration-resistant prostate cancer

Androgens i.e. testosterone (T) and dihydrotestosterone (DHT), have essential roles in the differentiation and growth of normal prostate cells, as well as in the progression of prostate cancer (PCa) cells. Androgen deprivation therapy (ADT) is an effective therapy for PCa patients, however, prostate tumor cells progress to a treatment-resistant stage ...
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Sema3a, Sema3c, Sema3f and Nrp1 genes expression associations with glioma progression and patient survival

2019
Glioma is the most common tumor in the central nervous system. The scientists try to find a way to inhibit tumor development and identify potential biomarkers for an earlier glioma prognosis. The aim of this study was to analyze the changes of SEMA3A, SEMA3C, SEMA3F, and NRP1 gene expression in different grade astrocytic glioma tumors and to identify ...
Kardonaitė, Deimantė, Valiulytė, Indrė, Tamašauskas, Arimantas, Kazlauskas, Arūnas   +3 more
openaire   +1 more source