Results 61 to 70 of about 2,835 (194)

From HBV to MASLD Cirrhosis: Mechanistic Insights and Therapeutic Strategies

Portal Hypertension &Cirrhosis, Volume 5, Issue 2, Page 170-188, June 2026.
This review examines the epidemiological shift from hepatitis B virus (HBV) to metabolic dysfunction‐associated steatotic liver disease (MASLD) as the leading cause of cirrhosis globally. It highlights the distinct pathogenic mechanisms between HBV and MASLD cirrhosis and discusses evolving diagnostic tools and therapeutic strategies tailored to the ...
Hanqi Yu, Hongfan Ding, Yang Huang, Haoze Cao, Yuan Ding, Weilin Wang   +5 more
wiley   +1 more source

Table_3_Mediating immunosuppressive functions: a new perspective on the complex immunological properties of SEMA4D in the tumor microenvironment.xlsx

, 2023
Semaphorin 4D (SEMA4D) is considered a new antitumor target closely related to immune cells. However, understanding the role of SEMA4D in the tumor microenvironment (TME) is limited.
Leping Li (20246), Zihao Zhang (2335846), Changqing Jing (6800879), Shujie Zeng (15833534), Chunshui Ye (12341117), Jinshen Wang (509366)   +5 more
core   +1 more source

Cytokine profiling in plasma distinguishes the histological inflammatory subtype of head and neck squamous cell carcinoma and a novel regulatory role of osteopontin

Frontiers in Oral Health, 2022
Head and neck squamous cell carcinoma (HNSCC) can be classified according to the histological inflammatory subtype (HIS) into inflamed (HIS-INF) or immune excluded (HIS-IE).
Ioana Ghita, Evangelia Piperi, Evangelia Piperi, Sergei P. Atamas, Soren M. Bentzen, Soren M. Bentzen, Soren M. Bentzen, Robert A. Ord, Robert A. Ord, Donita Dyalram, Donita Dyalram, Joshua E. Lubek, Joshua E. Lubek, Rania H. Younis, Rania H. Younis   +14 more
doaj   +1 more source

Estrogen increases levels of Sema4D mRNA, but not Plexin-B1 mRNA in mouse vagina.

, 2014
(A) Sema4D mRNA levels were significantly lower in vaginal tissues from OVX WT mice than in vaginal tissues from sham-operated mice. Based on comparisons between OVX-E2 and OVX-oil mice, OVX-E2 treatment induced a significant increase of Sema4D mRNA ...
Tetsuji Tanaka (566033), Kenji Yoshida (299416), Atsushi Kumanogoh (50659), Takuji Ito (566032), Takashi Ueyama (420503), Hyota Takamatsu (566036), Hitoshi Kikutani (50660), Masayasu Miyajima (184194), Kazunori Yukawa (566037), Takayuki Negishi (566034), Tao Bai (90717), Takahiko Kawasaki (566035)   +11 more
core   +1 more source

Table_1_Mediating immunosuppressive functions: a new perspective on the complex immunological properties of SEMA4D in the tumor microenvironment.docx

, 2023
Semaphorin 4D (SEMA4D) is considered a new antitumor target closely related to immune cells. However, understanding the role of SEMA4D in the tumor microenvironment (TME) is limited.
Leping Li (20246), Zihao Zhang (2335846), Changqing Jing (6800879), Shujie Zeng (15833534), Chunshui Ye (12341117), Jinshen Wang (509366)   +5 more
core   +1 more source

Epidemiology, Risk Factors and Pathophysiology of Primary Sclerosing Cholangitis in Inflammatory Bowel Disease: An Update

JCC Plus, Volume 1, Issue 3, May 2026.
ABSTRACT Background and Aims Primary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD) represent a unique clinical syndrome affecting up to 80% of PSC patients, characterised by distinct epidemiological patterns, pathophysiological mechanisms and clinical outcomes that differ substantially from either condition occurring independently ...
Luisa Bertin, Paul Henderson, Richard Pollok, Natália Queiroz, Luca Fabris, Edoardo Vincenzo Savarino, Iago Rodríguez‐Lago, Brigida Barberio   +7 more
wiley   +1 more source

DataSheet_1_Mediating immunosuppressive functions: a new perspective on the complex immunological properties of SEMA4D in the tumor microenvironment.docx

, 2023
Semaphorin 4D (SEMA4D) is considered a new antitumor target closely related to immune cells. However, understanding the role of SEMA4D in the tumor microenvironment (TME) is limited.
Leping Li (20246), Zihao Zhang (2335846), Changqing Jing (6800879), Shujie Zeng (15833534), Chunshui Ye (12341117), Jinshen Wang (509366)   +5 more
core   +1 more source

Overexpression of Semaphorin-3A and Semaphorin-4D in the Peripheral Blood from Newly Diagnosed Patients with Chronic Lymphocytic Leukemia

International Journal of Hematology-Oncology and Stem Cell Research, 2019
Background: Semaphorins play prominent roles in physiological and pathological processes such as vascular development, tumor growth and immune responses. Semaphorins have different roles in various kinds of cancers, but there is no study concerning their
Somayeh Parsa, Sedigheh Sharifzadeh, Ahmad Monabati, Noorossadat Seyyedi, Reza Ranjbaran, Mohammad Reza Baghbani, Maryam Nemati, Abdollah Jafarzadeh   +7 more
doaj   +1 more source

Evaluating Protein Enrichment Methods to Improve Biomarker Discovery in Equine Cerebrospinal Fluid

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Here, we compared two protein enrichment methods—ProteoMiner Small‐Capacity and PreOmics Enrich‐iST—for proteomic analysis of equine cerebrospinal fluid (CSF). PreOmics Enrich‐iST achieved superior depletion of high‐abundance proteins and identified a greater number of low‐abundance, neuropathology‐relevant proteins than ProteoMiner or native digestion.
Foti Federico, Wilson Amie, Chabronova Alzbeta, Jensen Anders, Lunn Paul David, Peffers Jayne Mandy   +5 more
wiley   +1 more source

Plasma Sema4D levels in HF patients with diabetes or hypertension.

, 2013
A. Plasma Sema4D levels in HF patients with or without diabetes mellitus (DM). B. Plasma Sema4D levels in HF patients with or without hypertension (HP) history. Each box represents the median and interquartile range values. The outliers that are >1.5 and
Xin Zhao (71840), Haibo Gu (417268), Qingyu Wu (147511), Shengjie Zhang (417267), Qi Wang (22418), Li Zhu (67404), Ningzheng Dong (328283), Yuxin Wang (414197), Wenxiu Yi (417266), Qiongyu Lu (417265), Boquan Jin (383395), Lawrence F. Brass (417270), Xiaorong Tang (417269)   +12 more
core   +1 more source