Results 131 to 140 of about 14,138 (186)

A bispecific antibody designed to act as a NRP2/PLXNA1 agonist mimics anticancer activity of SEMA3F. [PDF]

open access: yesJ Biol Chem
Tian H   +14 more
europepmc   +1 more source

Bronchopulmonary dysplasia with pulmonary hypertension associates with semaphorin signaling loss and functionally decreased FOXF1 expression. [PDF]

open access: yesNat Commun
Shirazi SP   +15 more
europepmc   +1 more source
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Semaphorins in cancer

Frontiers in Bioscience, 2005
The semaphorins are the products of a large family of genes currently containing more than 30 members. These genes are divided into eight classes of which classes 1, 2 and 8 contain invertebrate and viral semaphorins, while classes 3-7 contain the vertebrate semaphorins.
Gera, Neufeld   +5 more
openaire   +2 more sources

Semaphorins in health and disease

Cytokine & Growth Factor Reviews, 2021
Cell-cell communication is pivotal to guide embryo development, as well as to maintain adult tissues homeostasis and control immune response. Among extracellular factors responsible for this function, are the Semaphorins, a broad family of around 20 different molecular cues conserved in evolution and widely expressed in all tissues.
Damon Fard, Luca Tamagnone
openaire   +3 more sources

Control of semaphorin signaling

Current Opinion in Neurobiology, 2002
Receptor complexes for the chemorepellent factors of the semaphorin family activate intracellular pathways that trigger actin rearrangements underlying growth cone collapse and repellent behavior. Some evidence has been provided for a complex and dynamic pattern of interaction between members of the small Rho guanosine triphosphatases and plexin ...
Castellani, Valérie, Rougon, Geneviève
openaire   +4 more sources

Osteoprotection by semaphorin 3A

Nature, 2012
The bony skeleton is maintained by local factors that regulate bone-forming osteoblasts and bone-resorbing osteoclasts, in addition to hormonal activity. Osteoprotegerin protects bone by inhibiting osteoclastic bone resorption, but no factor has yet been identified as a local determinant of bone mass that regulates both osteoclasts and osteoblasts ...
Mikihito, Hayashi   +5 more
openaire   +2 more sources

Receptors for collapsin/semaphorins

Current Opinion in Neurobiology, 1998
Chemorepulsive signals that repel or paralyze neuronal growth cones have been found to play important roles in axon guidance in a stereotyped manner. Recent progress in the identification of neuropilins as the receptors for class III secreted collapsin/semaphorin subfamily members, which are neuronal repellents, and in the analysis of mutant mice ...
H, Fujisawa, T, Kitsukawa
openaire   +2 more sources

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