Structural bases for CRMP function in plexin‐dependent semaphorin3A signaling [PDF]
The EMBO Journal, 2003 Collapsin response mediator proteins (CRMPs) are cytosolic phosphoproteins involved in neuronal differentiation and axonal guidance. CRMP2 was previously shown to mediate the repulsive effect of Sema3A on axons and to participate in axonal specification.
Rahul C, Deo +5 more
openaire +2 more sources
Effects of mechanical repetitive load on bone quality around implants in rat maxillae. [PDF]
PLoS ONE, 2017 Greater understanding and acceptance of the new concept "bone quality", which was proposed by the National Institutes of Health and is based on bone cells and collagen fibers, are required.
Yusuke Uto +6 more
doaj +1 more source
Ovariectomy and subsequent treatment with estrogen receptor agonists tune the innate immune system of the hippocampus in middle-aged female rats. [PDF]
PLoS ONE, 2014 The innate immune system including microglia has a major contribution to maintenance of the physiological functions of the hippocampus by permanent monitoring of the neural milieu and elimination of tissue-damaging threats.
Miklós Sárvári +4 more
doaj +1 more source
The Involvement of Immune Semaphorins in the Pathogenesis of Inflammatory Bowel Diseases (IBDs). [PDF]
PLoS ONE, 2015 Immune semaphorins are a large family of proteins involved in the pathogenesis of inflammatory diseases through the regulation of immune homeostasis and tissue inflammation.
Zahava Vadasz +6 more
doaj +1 more source
Semaphorin3A signaling controls Fas (CD95)-mediated apoptosis by promoting Fas translocation into lipid rafts [PDF]
, 2008 Semaphorins and their receptors (plexins) have pleiotropic biologic functions, including regulation of immune responses. However, the role of these molecules inside the immune system and the signal transduction mechanism(s) they use are largely unknown ...
CATALANO, Alfonso +8 more
core +1 more source
GSK3β/Axin-1/β-Catenin Complex Is Involved in Semaphorin3A Signaling [PDF]
The Journal of Neuroscience, 2012 Semaphorin3A (Sema3A) exerts a wide variety of biological functions by regulating reorganization of actin and tubulin cytoskeletal proteins through signaling pathways including sequential phosphorylation of collapsin response mediator protein 1 (CRMP1) and CRMP2 by cyclin-dependent kinase-5 and glycogen synthase kinase-3β (GSK3β).
Tomonobu, Hida +6 more
openaire +2 more sources
, 2022 Background and Objective Identification of biomarkers to assess individual risk and monitor periodontal health status is important. Research on lipocalin-2 (LCN2) and semaphorin3A (Sema3A) is lacking.
Yilmaz, Huriye Erbak +9 more
core +1 more source
Growth of the human corpus callosum: modular and laminar morphogenetic zones
Frontiers in Neuroanatomy, 2009 The purpose of this focused review is to present and discuss recent data on the changing organization of cerebral midline structures that support the growth and development of the largest commissure in humans, the corpus callosum. We will put an emphasis
Natasa Jovanov-Milosevic +3 more
doaj +1 more source
Inhibition of Semaphorin3A Promotes Ocular Dominance Plasticity in the Adult Rat Visual Cortex [PDF]
, 2019 Perineuronal nets (PNNs) are condensed structures in the extracellular matrix that mainly surround GABA-ergic parvalbumin-positive interneurons in the adult brain. Previous studies revealed a parallel between PNN formation and the closure of the critical
Vander Kooi, Craig W. +15 more
core +1 more source
Journal of Pharmacological Sciences, 2011 .: Sneezing and persistent itching of the nasal mucosa are distressing symptoms of allergic rhinitis (AR). Recent studies have revealed that hyperinnervation of sensory neurons in the nasal turbinate is one of the underlying causes of sneezing and ...
Haruna Sawaki +8 more
doaj +1 more source