Results 31 to 40 of about 4,062 (156)
Biomedicines, 2022 Nonalcoholic fatty liver disease (NAFLD) is associated with systemic changes in immune response linked with chronic low-grade inflammation and disease progression.
Lara Šamadan +5 more
doaj +1 more source
Plexin B2 and Semaphorin 4C Guide T Cell Recruitment and Function in the Germinal Center
Cell Reports, 2017 Summary: Follicular T helper (TFH) cells orchestrate the germinal center (GC) response locally. TFH localization in GCs is controlled by chemo-guidance cues and antigen-specific adhesion. Here.
Hu Yan +13 more
doaj +1 more source
Bioactive Materials, 2022 Sensory nerves promote osteogenesis through the release of neuropeptides. However, the potential application and mechanism in which sensory nerves promote healing of bone defects in the presence of biomaterials remain elusive.
Yu-Xuan Ma +10 more
doaj +1 more source
Regulatory sequence analysis of semaphorin 4D 5' non-coding region. [PDF]
J Cancer, 2019 Semaphorin 4D (Sema4D) has been proven to be one of the hypoxia effectors regulated by hypoxia inducible factor (HIF-1) in multiple cells, and play a role in angiogenesis like VEGF. However, the regulatory sequence characteristics of the Sema4D are not clarified.
Qiu L +8 more
europepmc +4 more sources
Knockout of Sema4D alleviates liver fibrosis by suppressing AOX1 expression
Pharmacological Research, 2023 Liver fibrosis can occur in many chronic liver diseases, and no effective treatments are available due to the poorly characterized molecular pathogenesis. Semaphorin 4D (Sema4D) has immune functions and serves important roles in T cell priming.
Lifu Wang +9 more
doaj +1 more source
Neuroimmune semaphorin 4D is necessary for optimal lung allergic inflammation [PDF]
Molecular Immunology, 2013 Neuroimmune semaphorin 4D (Sema4D) was found to be expressed and function in the nervous and immune systems. In the immune system, Sema4D is constitutively expressed on T cells and regulates T cell priming. In addition, it displays a stimulatory function on macrophages, DC, NK cells, and neutrophils.
K, Shanks +7 more
openaire +2 more sources
Engineering, Characterization, and Biological Evaluation of an Antibody Targeting the HGF Receptor
Frontiers in Immunology, 2021 The Hepatocyte growth factor (HGF) and its receptor (MET) promote several physiological activities such as tissue regeneration and protection from cell injury of epithelial, endothelial, neuronal and muscle cells.
Claudia Desole +19 more
doaj +1 more source
Frontiers in Oncology, 2023 Semaphorin 4D (SEMA4D) is considered a new antitumor target closely related to immune cells. However, understanding the role of SEMA4D in the tumor microenvironment (TME) is limited.
Shujie Zeng +14 more
doaj +1 more source
Inflammatory Semaphorins in the Pathogenesis and Prognosis of Acute Ischemic Stroke
MedicinaBackground and Objectives: Semaphorins are immunoregulatory proteins involved in inflammation and neurovascular modulation. Their roles in ischemic stroke pathogenesis and prognosis have recently gained attention.
Esen Çiçekli +2 more
doaj +1 more source
Enterococcus faecalis promotes osteoclastogenesis and semaphorin 4D expression
Innate Immunity, 2015 Enterococcus faecalis is considered a major bacterial pathogen implicated in endodontic infections and contributes considerably to periapical periodontitis. This study aimed to investigate the potential mechanisms by which E. faecalis accounts for the bone destruction in periapical periodontitis in vitro.
Deng, Z +6 more
openaire +6 more sources