Results 21 to 30 of about 3,710 (118)
The Relationship Between Immune Semaphorins and Myasthenia Gravis [PDF]
Brain and BehaviorObjective Myasthenia gravis (MG) is an autoimmune disease involving several immune mechanisms. Recently, semaphorins have emerged as potential diagnostic and prognostic biomarkers in autoimmune neurological and non‐neurological diseases.
Dilcan Kotan +2 more
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Semaphorins in Adult Nervous System Plasticity and Disease
Frontiers in Synaptic Neuroscience, 2021 Semaphorins, originally discovered as guidance cues for developing axons, are involved in many processes that shape the nervous system during development, from neuronal proliferation and migration to neuritogenesis and synapse formation.
Daniela Carulli +3 more
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Association of Immune Semaphorins with COVID-19 Severity and Outcomes
Biomedicines, 2023 Semaphorins have recently been recognized as crucial modulators of immune responses. In the pathogenesis of COVID-19, the activation of immune responses is the key factor in the development of severe disease. This study aimed to determine the association
Martina Vargovic +4 more
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Semaphorin-7A is an erythrocyte receptor for P. falciparum merozoite-specific TRAP homolog, MTRAP.
PLoS Pathogens, 2012 The motility and invasion of Plasmodium parasites is believed to require a cytoplasmic actin-myosin motor associated with a cell surface ligand belonging to the TRAP (thrombospondin-related anonymous protein) family.
S Josefin Bartholdson +6 more
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Biomedicines, 2022 Nonalcoholic fatty liver disease (NAFLD) is associated with systemic changes in immune response linked with chronic low-grade inflammation and disease progression.
Lara Šamadan +5 more
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eLife, 2021 In mice, early exposure to environmental odors affects social behaviors later in life. A signaling molecule, Semaphorin 7A (Sema7A), is induced in the odor-responding olfactory sensory neurons.
Nobuko Inoue +6 more
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Sema7A/PlxnCl signaling triggers activity-dependent olfactory synapse formation
Nature Communications, 2018 The molecular mechanisms underlying synapse formation in the olfactory bulb are not fully understood. Here the authors demonstrate that semaphorin 7A on olfactory sensory neurons, and its receptor plexin C1 expressed on mitral and tufted cells, is ...
Nobuko Inoue +4 more
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Journal of Clinical and Translational Science, 2023 OBJECTIVES/GOALS: Estrogen receptor-positive (ER+) breast cancers (BC) comprise >70% of all BC and cause the most BC-related deaths in women worldwide.
Rachel Steinmetz, Traci Lyons
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Kidney Medicine, 2021 Technological advances have allowed the discovery of 6 subtypes of membranous nephropathy based on target antigens: M-type phospholipase A2 receptor (PLA2R), thrombospondin type 1 domain-containing 7A (THSD7A), neural epidermal growth factor-like 1 ...
Takamasa Iwakura +7 more
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Signaling mechanisms of the platelet glycoprotein Ib-IX complex
Platelets, 2022 The glycoprotein Ib–IX (GPIb-IX) complex mediates initial platelet adhesion to von Willebrand factor (VWF) immobilized on subendothelial matrix and endothelial surfaces, and transmits VWF binding-induced signals to stimulate platelet activation.
Yaping Zhang +3 more
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