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Measuring the Time-Scale-Dependent Information Flow Between Maternal and Fetal Heartbeats During the Third Trimester: Impact of Fetal Sex and Maternal Chronic Stress. [PDF]
Garnier NB +4 more
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"Brain doping" substances: prohibited or not in sports? [PDF]
Pokrywka A +7 more
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Effects of Semax in the Models of Acute Stress
Российский физиологический журнал им И М Сеченова, 2023Acute stress exposure causes a cascade of neurochemical reactions, leading, in particular, to a change in behavior and increased tolerance to pain in humans and animals. ACTH/MSH-like peptides play an important role in regulating the body’s response to stressful exposures.
N. Yu. Glazova +9 more
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Therapy of Peptic Ulcer with Semax Peptide
Bulletin of Experimental Biology and Medicine, 2002Experiments used is combination with traditional preparations (omeprasole, de-nol, and solcoseril), Semax peptide (Met-Glu-His-Phe-Pro-Gly-Pro) possessing nootropic and neuroprotective activity significantly promoted ulcer healing in patients with refractory peptic ulcers.
I O, Ivanikov +4 more
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Synthesis of tritium-labeled Semax
Radiochemistry, 2006The tert-butyloxycarbonyl derivative of Met-Glu-His-Phe-Pro-Gly was prepared and condensed with either unsaturated or labeled proline. The unsaturated peptide protected by the tert-butyloxycarbonyl group was hydrogenated with gaseous tritium in the presence of a catalyst.
V. P. Shevchenko +7 more
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Biology Bulletin, 2005
A comparative study of nootropic activity of semax (MEHFPGP), an analog of ACTH 4-10 , and some of its derivatives, in which the N-terminal methionine was modified or substituted with other amino acid residues, was performed. The effect of these peptides on learning of albino rats in tests with positive (food) and negative (pain) reinforcement was ...
N. Yu. Glazova +6 more
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A comparative study of nootropic activity of semax (MEHFPGP), an analog of ACTH 4-10 , and some of its derivatives, in which the N-terminal methionine was modified or substituted with other amino acid residues, was performed. The effect of these peptides on learning of albino rats in tests with positive (food) and negative (pain) reinforcement was ...
N. Yu. Glazova +6 more
openaire +1 more source
Effect of semax and semax-heparin mixture on isolated heart activity after total ischemia in rats
Bulletin of Experimental Biology and Medicine, 1999Semax administered after 40-min total ischemia of isolated heart improved the recovery of heart rate and reduced myocardial contracture. When administered prior to ischemia, Semax exerted a negative effect on recovery of heart contractility. Semax-heparin mixture significantly improved the recovery of cardiac indices (end-diastolic pressure, heart rate,
A. V. Orlov +5 more
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Effects of Semax on the Default Mode Network of the Brain
Bulletin of Experimental Biology and Medicine, 2018The effects of nootropic drug Semax on the neuronal network of the brain were studied by the resting state functional magnetic-resonance imaging (resting state fMRI). The study was carried out on two groups of healthy volunteers (11 men and 13 women aged 43.9±9.5 years). Resting state fMRI was carried out 3 times: directly before and 5 and 20 min after
I S, Lebedeva +6 more
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SEMAX - APPLICATION PROSPECTS (brief overview message)
Clinical Medicine and Pharmacology, 2021A brief overview report on the materials of domestic research, as a priority, shows a brief history of the study of regulatory peptides, in particular Semax. The need to continue scientific research in this direction is due, in addition to somatoform and psychosomatic diseases, complications of var-ious diseases in the form of memory impairment, a ...
Elena Belyaeva, K. Hadarceva
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Effect of semax heptapeptide on the human electroencephalogram
Bulletin of Experimental Biology and Medicine, 1996The effect of the new regulatory peptide Semax (ACTH4–10 fragment) on the electroencephalogram of a healthy person was studied. Semax was administered at 0.5 mg/kg intranasally in 9 volunteers without causing any nervous system pathology. The control group comprised 6 examinees treated in the same way with distilled water.
M. V. Koroleva +4 more
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