Results 21 to 30 of about 9,419 (207)

Triazolinediones as highly enabling synthetic tools [PDF]

open access: yes, 2016
Triazolinediones (TADs) are unique reagents in organic synthesis that have also found wide applications in different research disciplines, in spite of their somewhat "exotic" reputation.
Billiet, Stijn   +5 more
core   +1 more source

Presence of nitrofurans and their metabolites in gelatine

open access: yesEFSA Journal, 2021
Following the detection of semicarbazide (SEM) in gelatine by Italian Authorities, at levels exceeding by three times the reference point for action (RPA) of 1 μg/kg, set out by Commission Regulation (EU) 2019/1871 for nitrofurans and their metabolites ...
European Food Safety Authority (EFSA)   +3 more
doaj   +1 more source

Genomic and experimental evidence for multiple metabolic functions in the RidA/YjgF/YER057c/UK114 (Rid) protein family. [PDF]

open access: yes, 2015
BackgroundIt is now recognized that enzymatic or chemical side-reactions can convert normal metabolites to useless or toxic ones and that a suite of enzymes exists to mitigate such metabolite damage.
Cooper, Arthur JL   +8 more
core   +2 more sources

Association between plasma activities of semicarbazide-sensitive amine oxidase and angiotensin-converting enzyme in patients with type 1 diabetes mellitus [PDF]

open access: yes, 2005
Aims/hypothesis: Plasma semicarbazide-sensitive amine oxidase (SSAO) is elevated in patients with type 1 and type 2 diabetes and has been implicated in the pathophysiology of diabetic late complications. The regulation of SSAO production remains unknown.
Agerholm-Larsen, B. (B.)   +6 more
core   +1 more source

Effects of the food contaminant semicarbazide on testicular morphology of juvenile Wistar rats

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia, 2012
O objectivo do presente trabalho foi avaliar os efeitos da semicarbazida na morfologia testicular de ratos Wistar jovens. Os animais foram tratados durante 30 dias com hidrocloreto de semicarbazida incorporado na dieta, nas concentrações de 0, 3 e 6g/kg.
A Ramos   +3 more
doaj   +1 more source

Amine oxidases as important agents of pathological processes of rhabdomyolysis in rats [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2016
In this study we have tested an idea on the important role of amine oxidases (semicarbazide-sensitive amine oxidase, diamine oxidase, polyamine oxidase) as an additional source of oxidative/carbonyl stress under glycerol-induced rhabdomyolysis, since the
O. O. Gudkova   +2 more
doaj   +1 more source

Pharmacological and Structure-Activity Relationship Evaluation of 4-aryl-1-Diphenylacetyl(thio)semicarbazides [PDF]

open access: yes, 2014
This article describes the synthesis of six 4-aryl-(thio)semicarbazides (series a and b) linked with diphenylacetyl moiety along with their pharmacological evaluation on the central nervous system in mice and computational studies, including ...
Fidecka, Sylwia   +8 more
core   +2 more sources

Oral Administration of Semicarbazide Limits Weight Gain together with Inhibition of Fat Deposition and of Primary Amine Oxidase Activity in Adipose Tissue

open access: yesJournal of Obesity, 2011
An enzyme hitherto named semicarbazide-sensitive amine oxidase (SSAO), involved in the oxidation of primary amines, is abundantly expressed in adipocytes.
Josep Mercader   +3 more
doaj   +1 more source

Exploring Novel Pyridine Carboxamide Derivatives as Urease Inhibitors: Synthesis, Molecular Docking, Kinetic Studies and ADME Profile

open access: yesPharmaceuticals, 2022
The rapid development of resistance by ureolytic bacteria which are involved in various life-threatening conditions such as gastric and duodenal cancer has induced the need to develop a new line of therapy which has anti-urease activity.
Ayesha Naseer   +7 more
doaj   +1 more source

Synthesis and Biological Evaluation of 1-(2-(6-Methoxynaphthalen-2-yl)-6-methylnicotinoyl)-4-Substituted Semicarbazides/Thiosemicarbazides as Anti-Tumor Nur77 Modulators

open access: yesMolecules, 2022
Nur77 is an orphan nuclear receptor that participates in the occurrence and development of a variety of tumors. Many agonists of Nur77 have been reported to have significant anticancer effects.
Hongyu Hu   +7 more
doaj   +1 more source

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