Results 231 to 240 of about 666,129 (262)

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

AUF1 Restrains Hepatocyte Senescence by Maintaining Mitochondrial Homeostasis in AML12 Hepatocyte Model. [PDF]

Cells
Jung M, Han S, Ryu S, Cha S, Sim YE, Jung SH, Tak H, Kim W, Lee EK.   +8 more
europepmc   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

The Yin and Yang of cellular senescence in ischemia-induced myocardial injury. [PDF]

Trends Cardiovasc Med
Wolff von Gudenberg R, Iske J, Roeschl T, Stawowy P, Kirkland JL, Ruhparwar A, Tullius SG.   +6 more
europepmc   +1 more source

Age-independent and targetable transcription factor networks regulating CD8⁺ T cell senescence in aging humans. [PDF]

Cell Rep
Turano PS, Akbulut E, Dewald HK, Vasilopoulos T, Fitzgerald-Bocarsly P, Herbig U, Martínez-Zamudio RI.   +6 more
europepmc   +1 more source

Oxidative Stress and PRKN-Mediated Senescence Link RhoA/ROCK Signaling to Epithelial Remodeling in Allergic Rhinitis. [PDF]

Antioxidants (Basel)
Yuan X, Zhong W, Xie S, Liu L, Gu W, Zeng Y, Zhang H, Jiang W, Xie Z, Gao P.   +9 more
europepmc   +1 more source

Compartment-specific eccDNA patterns reveal senescence associated biomarkers in hUC-MSCs. [PDF]

Sci Rep
Yan Q, Xu Q, Yu Y, Wang D, Zhong W, Wu Y, Liu C, Xu Z, Fan D.   +8 more
europepmc   +1 more source

Enhancing cardiomyocyte reprogramming efficiency by targeting cellular senescence is mediated via Rb1 gene. [PDF]

Stem Cell Res Ther
Fang J, Yang Q, Maas RGC, Vader P, Mokry M, van den Dungen NAM, Qian L, Xiao J, Schiffelers R, Lei Z, Sluijter JPG.   +10 more
europepmc   +1 more source