Results 121 to 130 of about 1,495 (185)

Mitochondrial priming in therapy-induced senescence: implications for CAR-T/NK immunosenolytic therapy. [PDF]

Front Immunol
Menendez JA, Lupu R, Martin-Castillo B, Sardanyés J, Alarcón T, Verdura S, Cuyàs E.   +6 more
europepmc   +1 more source

Quercetin induces senolysis of doxorubicin-induced senescent fibroblasts by reducing autophagy, preventing their pro-tumour effect on osteosarcoma cells [PDF]

Bientinesi, Elisa, Lulli, Matteo, Monti, Daniela, Ristori, Sara   +3 more
core   +1 more source

Investigating the bidirectional interactions between senotherapeutic agents and human gut microbiota [PDF]

Biological ageing is a time-dependent process that has implications for health and disease. Cellular senescence is a key driver in ageing and age-related diseases.
Basit, Abdul W, Favaron, Alessia, Gaisford, Simon, Mai, Yang, McCoubrey, Laura E, Sangfuang, Nannapat, Taub, Marissa, Xie, Yuan   +7 more
core  

Selective Senolysis of 5FU-Induced CRC Senescent Cells by Piceatannol Through Mitochondrial Depolarization and AIF-Dependent Apoptosis. [PDF]

Int J Mol Sci
Ambrosino A, Patrone D, Moriello C, Al-Sammarraie SHA, Lettiero I, Finicelli M, Siniscalco D, Alessio N.   +7 more
europepmc   +1 more source

Targeting Cellular Senescence to Enhance Human Endometrial Stromal Cell Decidualization and Inhibit Their Migration [PDF]

Cellular senescence leads to stable cell cycle arrest and an inflammatory senescence-associated secretory phenotype that varies with stressor and cell type. To mitigate these effects and improve health, senotherapeutics (e.g., senolytics and senomorphics)

core   +1 more source

Supramolecular delivery of senolytics enables targeted anti-senescence therapy and accelerated fracture healing. [PDF]

J Nanobiotechnology
Fan Y, Wang ZH, Zhang X, Dong Y, Liu X, Luo G, Yang H, Li H, Wang Z, Tang Q, Jin X, Guo DS, Sun T.   +12 more
europepmc   +1 more source

Mechanistic insights into age-associated  chromosome mis-segregation and senescence [PDF]

, 2022
Monika Barroso Vilares
core  

Therapy-Induced Senescence Shapes Extracellular Matrix Niches and Fibroblast Function in Head and Neck Squamous Cell Carcinoma. [PDF]

Cancers (Basel)
Montero-Vergara J, Darski PW, Harding AL, Hunter KD.   +3 more
europepmc   +1 more source

Anti-senescence therapies: a new concept to address cardiovascular disease. [PDF]

Cardiovasc Res
Stojanović SD, Thum T, Bauersachs J.
europepmc   +1 more source

Low hyper-oxygen exposure induces p21-dependent p53-independent senescence in alveolar cells. [PDF]

Int J Med Sci
Lee CH, Lin KH, Lee MS, Lin CJ, Yang RC, Wang SC, Hsu CS, Kao JK.   +7 more
europepmc   +1 more source