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The Role of Senescence-Associated Secretory Phenotype in Bone Loss [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2022
As the population of most nations have a large proportion of older individuals, there is an increase in the prevalence of osteoporosis. Consequently, scientists have focused their attention on the pathogenic mechanisms of osteoporosis. Owing to an increase in studies on cellular senescence in recent years, research has begun to focus on the function of
Bin Yu, Yu Chai
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Some of the next articles are maybe not open access.

Controlling the senescence-associated secretory phenotype

Nature Reviews Molecular Cell Biology, 2016
Paulina Strzyz
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Methionine restriction delays senescence and suppresses the senescence-associated secretory phenotype in the kidney through endogenous hydrogen sulfide

open access: yesCell Cycle, 2019
Aging is a risk factor for various acute and chronic kidney injuries. Kidney aging is accompanied by the secretion of growth factors, proteases, and inflammatory cytokines, known as the senescence-associated secretory phenotype (SASP).
Guang-Yan Cai   +2 more
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Pro- and anti-tumorigenic functions of the senescence-associated secretory phenotype

open access: yesExpert Opinion on Therapeutic Targets, 2019
Introduction: Cellular senescence is a stable form of cell cycle exit. Though they no longer divide, senescent cells remain metabolically active and secrete a plethora of proteins collectively termed the senescence-associated secretory phenotype (SASP).
Gregory David
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Senescence-Associated Secretory Phenotype as a Hinge Between Cardiovascular Diseases and Cancer

Frontiers in Cardiovascular Medicine, 2021
Jun-Ichi Abe, Sivareddy Kotla
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Histone Variant H2A.J Marks Persistent DNA Damage and Triggers the Secretory Phenotype in Radiation-Induced Senescence

International Journal of Molecular Sciences, 2020
Carl Mann   +2 more
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