Results 121 to 130 of about 728 (163)

Intervention treatment reducing cellular senescence inhibits tubulointerstitial fibrosis in diabetic mice following acute kidney injury. [PDF]

Clin Sci (Lond)
Tesch GH, Ma FY, Ozols E, Nikolic-Paterson DJ.   +3 more
europepmc   +1 more source

Senolytic Therapy in Sleep Apnea: Murky Waters or Fountain of Youth? [PDF]

Am J Respir Crit Care Med
Jun JC.
europepmc   +1 more source

Pentraxin 3 deficiency ameliorates streptozotocin-induced pancreatic toxicity via regulating ER stress and β-cell apoptosis. [PDF]

Mol Cells
Kim S, Hwang AR, Kim SH, Lim JH, Woo CH.
europepmc   +1 more source

Inhibition of serotonin-Htr2b signaling in skeletal muscle mitigates obesity-induced insulin resistance. [PDF]

Exp Mol Med
Park S, Kim H, Shin S, Kim Y, Kang Y, Cha HN, Park SY, Park S, Oh CM.   +8 more
europepmc   +1 more source

Cellular senescence in colorectal cancer: its occurrence, effect and therapy. [PDF]

Front Oncol
Liang Y, Wang M, Wang X, Yang Z, Wang S, Li F, Su L, Yang L.   +7 more
europepmc   +1 more source

Drinking from the fountain of youth for mTOR-related epilepsy. [PDF]

Epilepsy Curr
Wong JC.
europepmc   +1 more source

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Senotherapy, cancer, and aging.

Journal of Geriatric Oncology, 2023
INTRODUCTION We aimed to highlight the effects of senotherapy on the prevention and treatment of cancer in older individuals. The aim of senotherapy is to eliminate senescent cells. These cells express the senescence-associated secretory phenotype (SASP).
Lodovico Balducci, C. Falandry, Silvio Monfardini   +2 more
semanticscholar   +5 more sources

Senotherapy: a new horizon for COPD therapy.

Chest, 2020
There is increasing evidence that COPD is a disease of accelerated lung aging, with the accumulation of senescent cells, which lose their ability to repair and secrete multiple inflammatory proteins known as the senescence-associated secretory phenotype (
J. Baker, L. Donnelly, P. Barnes
semanticscholar   +2 more sources

Senotherapy: Implications for Transplantation.

Transplantation
Cellular senescence has been identified as a potential driver of age-associated loss of organ function and as a mediator of age-related disease. Novel strategies in targeting senescent cells have shown promise in several organ systems to counteract ...
Martin Jaros, A. Melk
semanticscholar   +2 more sources