Cellular senescence in cancer: Unveiling dual roles, tumor microenvironment dynamics and therapeutic innovations (Review). [PDF]
Oncol LettLam Y, Gu J, Yin P.
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OSA and Accelerated Aging: An Overarching Pathway Driving End-Organ Morbidity and Mortality. [PDF]
Arch BronconeumolBadran M, Gozal D.
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Effects of low-intensity endurance exercise and low-dose lithium chloride administration on muscle atrophy in high-fat diet induced obese rats. [PDF]
Phys Act NutrJung SR.
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Senescent Cell Clearance Ameliorates Temporal Lobe Epilepsy and Associated Spatial Memory Deficits in Mice. [PDF]
Ann NeurolKhan T +12 more
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Older adults with cancer and common comorbidities-challenges and opportunities in improving their cancer treatment outcomes. [PDF]
J Natl Cancer InstChen W +7 more
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Eliminating senescent cells by white adipose tissue-targeted senotherapy alleviates age-related hepatic steatosis through decreasing lipolysis. [PDF]
GeroscienceTang Q +9 more
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Targeting p21 for diabetes: Another choice of senotherapy
Targeting p21 for diabetes: Another choice of senotherapySenotherapy, the elimination of senescent cells, is a cutting-edge treatment for aging-related and lifestyle diseases. In this issue of Cell Metabolism, Wang et al. report that p21[Cip1] highly expressing cells, which represent a senescent cell population, occur in the adipose tissue during obesity.
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Procyanidin B2-induced LKB1-AMPK activation mitigates vascular smooth muscle cell proliferation through inhibition of mTOR signaling. [PDF]
Korean J Physiol PharmacolPark HY +4 more
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The interconnections between gerontogen, aging, and senotherapy
Journal of Applied Pharmaceutical ScienceRahma Rahma, Agian Jeffilano Barinda
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Chronic Kidney Disease and Cellular Senescence. [PDF]
Int J Mol SciMorevati M +5 more
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