Results 91 to 100 of about 276 (129)
Consequences of senotherapies for tissue repair and reprogramming
Translational Medicine of Aging, 2019 Van Vliet, T., Kohli, J., Demaria, M.
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Senoprevention and senotherapy – new pharmacological strategies for age-related diseases?
Farmacja PolskaStarzenie organizmu jest procesem, który zależy od wielu czynników, a charakterystyczne cechy starzenia się ujawniają swój postęp na trzech różnych poziomach: molekularnym, komórkowym oraz systemowym. Starzenie komórek to złożony proces, regulowany czynnikami genetycznymi, epigenetycznymi i środowiskowymi, charakteryzujący wiele typów komórek ...
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The interconnections between gerontogen, aging, and senotherapy
Journal of Applied Pharmaceutical ScienceRahma Rahma, Agian Jeffilano Barinda
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The senescence–immune axis as a target for combining immunotherapy and senotherapy
Fernanda Saez-Calazans +4 more
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Cleaning, Chasing and Calming: Promising Paradigms of Senotherapy in Aging-Related Diseases
Shanshan Li +8 more
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ISTA strategy: A hierarchical nanosystem empowers sequential senotherapy in lung cancer
Pingyi Yao +10 more
core +1 more source
Healthy Ageing and Longevity, 2020 Cellular senescence is a stress and repair response that protects us from cancer and contributes to tissue homeostasis by inducing a stable cell cycle arrest and imposing a secretory phenotype. Senescent cells are held in check to avoid their aberrant proliferation while at the same time they serve as new signaling nodes to orchestrate tissue repair ...
Pilar Picallos-Rabina +2 more
exaly +3 more sources
Senotherapy, cancer, and aging
Journal of Geriatric OncologyWe aimed to highlight the effects of senotherapy on the prevention and treatment of cancer in older individuals. The aim of senotherapy is to eliminate senescent cells. These cells express the senescence-associated secretory phenotype (SASP). With production of inflammatory cytokines, growth factors, and different type of proteases, the SASP is ...
Silvio Monfardini
exaly +6 more sources