Results 71 to 80 of about 276 (129)
Ignoring the planet: A critical blind spot for research on ageing
Journal of Internal Medicine, Volume 298, Issue 6, Page 578-590, December 2025.Abstract Although research on ageing has largely concentrated on understanding the fundamental biology of the ageing process and devising pharmaceutical interventions in order to slow it down, increasing evidence has underscored the crucial role of environmental inputs across the life course and across generations, in shaping both individual and ...
Paul Shiels +6 more
wiley +1 more source
Cellular Senescence and Immunosenescence in Melanoma: Insights From the Tumor Microenvironment
Cancer Medicine, Volume 14, Issue 17, September 2025.ABSTRACT Background Melanoma is one of the most immunogenic malignancies, yet resistance to immune checkpoint inhibitors (ICIs) remains a major obstacle to durable therapeutic success. Emerging evidence indicates that aging‐related processes, including cellular senescence and immunosenescence, can reshape the tumor microenvironment (TME) to favor ...
Lihua Xiong, Jian Cheng
wiley +1 more source
Translational Medicine of Aging, 2023 Chronic aging represents the leading risk factor for the vast majority of age-related diseases, which together contribute to increased morbidities and elevated mortalities in late life. Senescent cells are highly associated with organismal aging and pathological conditions, and can be selectively targeted to delay aging process.
openaire +2 more sources
A Senolytic Strategy for Metabolic Health: Why the Endothelium Matters
iNew Medicine, Volume 2, Issue 1, March 2026.
He Liang +3 more
wiley +1 more source
Editorial: The Role of Cellular Senescence in Health and Disease
Frontiers in Cellular Neuroscience, 2022 Ignacio Palmero +8 more
doaj +1 more source
β‐Galactosidase Based Molecular Imaging for Visualization of Cellular Senescence
iRADIOLOGY, Volume 4, Issue 1, Page 63-65, February 2026.
Jiani Huang +3 more
wiley +1 more source
Senoterapia: una nueva perspectiva para el tratamiento de enfermedades neurodegenerativas [PDF]
, 2021 La senoterapia abarca todas aquellas estrategias terapéuticas dirigidas contra las células senescentes y/o el fenotipo secretor. La senescencia celular es un estado que se caracteriza por la detención permanente del ciclo celular, resistencia a la ...
core
Cellular senescense: an overview on characteristics, effects and senotherapy
Cellular senescence is defined as part of the aging process that can be found throughout the life cycle and, i tis linked to age-related chronic pathologies like diabetes, Alzheimer’s, Osteoporosis, Cancer and many others.
Ferreira, Patrícia dos Santos
core +1 more source
PharmaceuticsBackground/Objectives: With the rapid aging of the global population, the interest in therapies for age-related diseases has increased substantially. The skin is particularly important, as aging-related changes are visible and negatively impact quality ...
Seokmuk Park +6 more
doaj +1 more source
From Lasers to Longevity: Exploring Energy-Based Devices as Senotherapeutic Tools in Dermatology
CosmeticsBackground: Cutaneous aging is a multifactorial process, increasingly understood through the lens of cellular senescence, a state of stable cell cycle arrest accompanied by a pro-inflammatory secretory phenotype that disrupts tissue homeostasis.
Oana Mihaela Condurache Hrițcu +4 more
doaj +1 more source