Results 121 to 130 of about 767 (193)

Adoptive NK cell therapy: a potential revolutionary approach in longevity therapeutics

Immunity & Ageing
The aging process intricately involves immune system dynamics, with a crucial role in managing senescent cells (SNCs) and their senescence-associated secretory phenotypes (SASPs).
Xuewen Deng, Hiroshi Terunuma
doaj   +1 more source

Biochemical and transcriptomic evaluation of a 3D lung organoid platform for pre-clinical testing of active substances targeting senescence [PDF]

Chronic lung diseases such as chronic obstructive pulmonary disease and cystic fibrosis are incurable. Epithelial senescence, a state of dysfunctional cell cycle arrest, contributes to the progression of such diseases.
Bals, Robert, Beisswenger, Christoph, Brand, Michelle, Herr, Christian, Kattler, Kathrin, Kirsch, Susanne H., Milasius, Deivydas, Müller, Rolf, Ritzmann, Felix, Yao, Yiwen, Yildiz, Daniela   +10 more
core   +1 more source

Consequences of senotherapies for tissue repair and reprogramming

Translational Medicine of Aging, 2019
Van Vliet, T., Kohli, J., Demaria, M.
openaire   +2 more sources

Cellular Senescence as a Risk Factor in Head and Neck Cancer-Diagnostic and Therapeutic Perspective. [PDF]

Cancers (Basel)
Stachowiak M, Kostrzewa M, Golusinski W, Golusinski P, Golusinska-Kardach E, Masternak MM, Rubiś B.   +6 more
europepmc   +1 more source

Bcl-xL Inhibition Disrupts p27 Stability and Promotes Senescence Escape: Insights for Cancer Senotherapy

Abstract Purpose: Cellular senescence serves as a double-edged sword in oncology, acting as a tumor suppressor and a promoter of a pro-tumorigenic environment post-chemotherapy, necessitating targeted removal strategies.
Xiaobai He, Xiaopan Chen, XinYi Qian, Di Cui, SongLin Zhang, Xiuli Yang, Weijiao Fan, Nan Huang, Miaomiao Du, Linjie Chen, Leixiang Yang   +10 more
openaire   +1 more source

Author Correction: Inhibition of serotonin-Htr2b signaling in skeletal muscle mitigates obesity-induced insulin resistance. [PDF]

Exp Mol Med
Park S, Kim H, Shin S, Kim Y, Kang Y, Cha HN, Park SY, Park S, Oh CM.   +8 more
europepmc   +1 more source

The drug discovery and therapeutic nano-strategies targeting cellular senescence. [PDF]

Mater Today Bio
Wang Y, Liu M, Chen X, Wang S, Li J, Sun Y, Zheng X, Zhang J, Li H.   +8 more
europepmc   +1 more source

Cellular senescence in cancer: Unveiling dual roles, tumor microenvironment dynamics and therapeutic innovations (Review). [PDF]

Oncol Lett
Lam Y, Gu J, Yin P.
europepmc   +1 more source

OSA and Accelerated Aging: An Overarching Pathway Driving End-Organ Morbidity and Mortality. [PDF]

Arch Bronconeumol
Badran M, Gozal D.
europepmc   +1 more source

Targeting Cellular Senescence with Liposome-Encapsulated Fisetin: Evidence of Senomorphic Effect. [PDF]

Int J Mol Sci
Henschke A, Grześkowiak B, Ivashchenko O, Sánchez-Cerviño MC, Coy E, Moya S.   +5 more
europepmc   +1 more source