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Apoptosis-coupled senescence causes cancer cell senotherapy
2023Abstract Although new generations of anti-cancer modalities have been accumulated involving immuno-oncology cancers remain prevailing. This implies the current understanding of cancer cell biology is far from satisfactory. Curation of cancers is extremely rare.
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Biochemical Society Transactions
Cellular senescence, a form of terminal cell cycle arrest, is as a key driver of organismal ageing and an important factor in age-related diseases. Insights into the senescent phenotype have led to the development of novel therapeutic strategies, collectively known as senotherapies, that aim to ameliorate the detrimental effects of senescent cell ...
Vinesh Dhokia +4 more
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Cellular senescence, a form of terminal cell cycle arrest, is as a key driver of organismal ageing and an important factor in age-related diseases. Insights into the senescent phenotype have led to the development of novel therapeutic strategies, collectively known as senotherapies, that aim to ameliorate the detrimental effects of senescent cell ...
Vinesh Dhokia +4 more
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Senotherapy as a Novel Therapeutic Method in Cancer Treatment: With a Focus on Head and Neck Cancer
Interdisciplinary cancer research, 2023Heliya Ziaei +2 more
exaly
Lineage-guided senescence insights unlock precision senotherapy
Aging ResearchZiqi Kang +3 more
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El papel patológico de las células senescentes está bien establecido en una variedad de enfermedades. A pesar de la amplia evidencia sobre el papel central que las mitocondrias desempeñan en la senescencia celular, la comprensión de las adaptaciones en las mitocondrias de las células senescentes es bastante superficial.
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