Results 111 to 120 of about 136,827 (244)

Microbial‐Metabolite Signatures Are Associated With Glucocorticoid Responsiveness in Chronic Rhinosinusitis With Nasal Polyps

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) exhibit heterogeneous responses to oral glucocorticoids (GCs), but the biological basis of this variability remains unclear. Objective To identify gut microbiome‒plasma metabolomic signatures associated with GC responsiveness in CRSwNP patients and to compare their ...
Ying‐Ying Zhang, Xin‐Yu Ding, Mei‐Ping Lu, Yan‐Bing Chen, Ye Yuan, Lin Jiang, Min Zhang, Lei Cheng   +7 more
wiley   +1 more source

Deficits in Prenatal Serine Biosynthesis Underlie the Mitochondrial Dysfunction Associated with the Autism-Linked FMR1 Gene. [PDF]

Int J Mol Sci, 2021
Nolin SL, Napoli E, Flores A, Hagerman RJ, Giulivi C.   +4 more
europepmc   +1 more source

Diversified amino acid-mediated allosteric regulation of phosphoglycerate dehydrogenase for serine biosynthesis in land plants. [PDF]

Biochem J, 2021
Okamura E, Ohtaka K, Nishihama R, Uchida K, Kuwahara A, Mochida K, Hirai MY.   +6 more
europepmc   +1 more source

In Vivo Evidence for Serine Biosynthesis-Defined Sensitivity of Lung Metastasis, but Not of Primary Breast Tumors, to mTORC1 Inhibition. [PDF]

Mol Cell, 2021
Rinaldi G, Pranzini E, Van Elsen J, Broekaert D, Funk CM, Planque M, Doglioni G, Altea-Manzano P, Rossi M, Geldhof V, Teoh ST, Ross C, Hunter KW, Lunt SY, Grünewald TGP, Fendt SM.   +15 more
europepmc   +1 more source

STUDIES ON THE MECHANISM OF THE BIOSYNTHESIS OF SERINE

Journal of Biological Chemistry, 1952
C, MITOMA, D M, GREENBERG
openaire   +2 more sources

Astrocytic PI3Kα controls synaptic plasticity and cognitive function via serine metabolism

Nature Communications
Astrocytes modulate neuronal activity by gliotransmission and through metabolic regulation, yet the relationship between these functions remains poorly understood.
Alba Fernández-Rodrigo, Celia García-Vilela, Abel Eraso-Pichot, Irene B. Maroto, María D. G. Moreno, Esperanza López-Merino, Silvia Gutiérrez-Eisman, Carla Sánchez-Castillo, Cristina Boers-Escuder, Eneko Merino-Casamayor, Mariona Graupera, Albert Quintana, María I. Cuartero, Maite Solas, Giovanni Marsicano, José A. Esteban   +15 more
doaj   +1 more source

Genetic disruption of serine biosynthesis is a key driver of macular telangiectasia type 2 aetiology and progression. [PDF]

Genome Med, 2021
Bonelli R, Ansell BRE, Lotta L, Scerri T, Clemons TE, Leung I, MacTel Consortium, Peto T, Bird AC, Sallo FB, Langenberg C, Bahlo M.   +11 more
europepmc   +1 more source

Regulation of Serine Biosynthesis in Arabidopsis [PDF]

Journal of Biological Chemistry, 1999
Chai-Ling Ho, Massaki Noji, Maiko Saito, Kazuki Saito   +3 more
openaire   +1 more source

Dietary Serine Supplementation Improves Growth Performance, Intramuscular Fat Content, and Composition of Gut Microbes and Metabolites in Growing–Finishing Pigs

Agriculture
Serine is widely involved in antioxidant synthesis, immune response, and fat metabolism. However, it remains unclear whether dietary serine supplementation affects fat deposition in the skeletal muscles of pigs.
Yiting Guo, Fang He, Zhiying Deng, Jie Yin, Guiping Guan, Zhengjun Xie, Xihong Zhou   +6 more
doaj   +1 more source

Plastidic Pathway of Serine Biosynthesis [PDF]

Journal of Biological Chemistry, 1999
Chai-Ling Ho, Massaki Noji, Kazuki Saito
openaire   +1 more source