Results 101 to 110 of about 451,320 (176)

Molecular and biochemical characterization of subtilisin-like proteases in arabidopsis thaliana [PDF]

, 2000
Subtilisin-like proteases form a large group of serine proteases with diverse functions, including the specific processing of a variety of proproteins and prohormones, and are found in prokaryotic and eukaryotic organisms. The work in this thesis focuses
Hamilton, John Michael Uwe
core  

Plastidic Pathway of Serine Biosynthesis [PDF]

Journal of Biological Chemistry, 1999
Chai-Ling Ho, Massaki Noji, Kazuki Saito
openaire   +1 more source

Impaired glycolysis-derived serine metabolism as a key driver of podocyte injury with senescence

Nature Communications
Chronic kidney disease (CKD) is a major health issue, with podocyte injury with senescence playing a central role in glomerulosclerosis. This study investigates the link between glycolysis-derived serine metabolism and podocyte injury with senescence ...
Hongtu Hu, Zijing Zhu, Lanlan Li, Jijia Hu, Qian Yang, Zhuan Peng, Weiwei Li, Xiaofei Cui, Yanqin Fan, Wenjie Chen, Wei Liang, Zhaowei Chen, Guohua Ding   +12 more
doaj   +1 more source

Preclinical efficacy of CBR-5884 against epithelial ovarian cancer cells by targeting the serine synthesis pathway

Discover Oncology
Reprogramming of the serine synthesis pathway (SSP) is intricately linked to the progression of epithelial ovarian cancer (EOC). CBR-5884, a selective small-molecule inhibitor targeting phosphoglycerate dehydrogenase (PHGDH), effectively impedes the de ...
Kunxiang Gong, Yinger Huang, Yanqin Zheng, Yinfu Zhu, Wenbo Hao, Kun Shi   +5 more
doaj   +1 more source

Characterization of L­-Serine O-succinyltransferases involved in l-cysteine biosynthesis in prokaryotes

, 2018
International audienceUntil very recently, acetylation was the only known way for activating L-serine in the penultimate step of L-cysteine biosynthesis, in bacteria and fungi.
Perret, Alain, de Berardinis, Véronique, Mariage, Aline, Bazire, Pascal, Bastard, Karine, Bessonnet, Thomas, Darii, Ekaterina, Petit, Jean-Louis   +7 more
core   +2 more sources

Brucella abortus Depends on l-Serine Biosynthesis for Intracellular Proliferation. [PDF]

Infect Immun, 2020
Révora V, Marchesini MI, Comerci DJ.
europepmc   +1 more source

Biosynthesis of fluoroacetate and 4-fluorothreonine in Streptomyces cattleya [PDF]

, 1996
This thesis describes results on the biosynthesis of fluoroacetate and 4-fluorothreonine by the bacterium Streptomyces cattleya. Exploratory (^14)C-radiolabelling experiments, designed to determine the relative incorporation of a range of metabolites ...
Amin, Muhammad Ruhul
core  

De novo serine biosynthesis is protective in mitochondrial disease

, 2023
Jackson CB, Marmyleva A, Awadhpersad R, Monteuuis G, Mito T, Zamboni N, Tatsuta T, Vincent AE, Wang L, Langer T, Carroll CJ, Suomalainen A.   +11 more
europepmc   +1 more source

On the role played by formate in serine biosynthesis [PDF]

Biochemical Journal, 1951
openaire   +2 more sources

ILF3 is a substrate of SPOP for regulating serine biosynthesis in colorectal cancer. [PDF]

Cell Res, 2020
Li K, Wu JL, Qin B, Fan Z, Tang Q, Lu W, Zhang H, Xing F, Meng M, Zou S, Wei W, Chen H, Cai J, Wang H, Zhang H, Cai J, Fang L, Bian X, Chen C, Lan P, Ghesquière B, Fang L, Lee MH.   +22 more
europepmc   +1 more source