Results 81 to 90 of about 451,320 (176)

Aspergillus westerdijkiae polyketide synthase gene “aoks1” is involved in the biosynthesis of ochratoxin A [PDF]

, 2009
OchratoxinA (OTA) is a potential nephrotoxic, teratogenic, immunogenic, hepatotoxic and carcinogenic mycotoxin, produced by Aspergillus westerdijkiae NRRL 3174.
Atoui, Ali, Mathieu, Florence, Liboz, Thierry, Bacha, Nafees, Lebrihi, Ahmed   +4 more
core   +1 more source

AMPK-HIF-1α signaling enhances glucose-derived de novo serine biosynthesis to promote glioblastoma growth. [PDF]

J Exp Clin Cancer Res, 2023
Yun HJ, Li M, Guo D, Jeon SM, Park SH, Lim JS, Lee SB, Liu R, Du L, Kim SH, Shin TH, Eyun SI, Park YY, Lu Z, Lee JH.   +14 more
europepmc   +1 more source

L-serine biosynthesis in the human central nervous system: Structure and function of phosphoserine aminotransferase. [PDF]

Protein Sci, 2023
Marchesani F, Zangelmi E, Murtas G, Costanzi E, Ullah R, Peracchi A, Bruno S, Pollegioni L, Mozzarelli A, Storici P, Campanini B.   +10 more
europepmc   +1 more source

Adult diagnosis of congenital serine biosynthesis defect: A treatable cause of progressive neuropathy. [PDF]

Am J Med Genet A, 2021
Debs S, Ferreira CR, Groden C, Kim HJ, King KA, King MC, Lehky T, Cowen EW, Brown LH, Merideth M, Owen CM, Macnamara E, Toro C, Gahl WA, Soldatos A.   +14 more
europepmc   +1 more source

De novo serine biosynthesis from glucose predicts sex-specific response to antifolates in non-small cell lung cancer cell lines. [PDF]

iScience, 2022
Sponagel J, Devarakonda S, Rubin JB, Luo J, Ippolito JE.   +4 more
europepmc   +1 more source

The Serine Biosynthesis of Paenibacillus polymyxa WLY78 Is Regulated by the T-Box Riboswitch. [PDF]

Int J Mol Sci, 2021
Zhang H, Li Q, Li Y, Chen S.
europepmc   +1 more source

Biosynthesis of serine in Neurospora crassa [PDF]

, 1973
Two pathways for serine biosynthesis in Neurospora crassa have been reported by Sojka and Garner. The phosphorylated pathway involves 3-phosphoglyceric acid, phosphohydroxypyruvic acid, and phosphoserine as intermediates, whereas the non-phosphorylated ...
Kline, Fereshteh Khosravi
core  

Serine biosynthesis defect due to haploinsufficiency of PHGDH causes retinal disease. [PDF]

Nat Metab, 2021
Eade K, Gantner ML, Hostyk JA, Nagasaki T, Giles S, Fallon R, Harkins-Perry S, Baldini M, Lim EW, Scheppke L, Dorrell MI, Cai C, Baugh EH, Wolock CJ, Wallace M, Berlow RB, Goldstein DB, Metallo CM, Friedlander M, Allikmets R.   +19 more
europepmc   +1 more source

Increased formate overflow is a hallmark of oxidative cancer

Nature Communications, 2018
Serine catabolism to formate supplies one-carbon units for biosynthesis. Here the authors show that formate production in murine cancers with high oxidative metabolism exceeds the biosynthetic demand and that high formate levels promotes invasion of ...
Johannes Meiser, Anne Schuster, Matthias Pietzke, Johan Vande Voorde, Dimitris Athineos, Kristell Oizel, Guillermo Burgos-Barragan, Niek Wit, Sandeep Dhayade, Jennifer P. Morton, Emmanuel Dornier, David Sumpton, Gillian M. Mackay, Karen Blyth, Ketan J. Patel, Simone P. Niclou, Alexei Vazquez   +16 more
doaj   +1 more source

Serine Biosynthesis Is a Metabolic Vulnerability in IDH2-Driven Breast Cancer Progression. [PDF]

Cancer Res, 2021
Barnabas GD, Lee JS, Shami T, Harel M, Beck L, Selitrennik M, Jerby-Arnon L, Erez N, Ruppin E, Geiger T.   +9 more
europepmc   +1 more source