Ankyrin-mediated self-protection during cell invasion by the bacterial predator Bdellovibrio bacteriovorus [PDF]
, 2015 Predatory Bdellovibrio bacteriovorus are natural antimicrobial organisms, killing other bacteria by whole-cell invasion. Self-protection against prey-metabolizing enzymes is important for the evolution of predation.
AA Russo +36 more
core +4 more sources
Pharmaceutically modified subtilisins withstand acidic conditions and effectively degrade gluten in vivo [PDF]
, 2019 Detoxification of gluten immunogenic epitopes is a promising strategy for the treatment of celiac disease. Our previous studies have shown that these epitopes can be degraded in vitro by subtilisin enzymes derived from Rothia mucilaginosa, a natural ...
Darwish, Ghassan +4 more
core +1 more source
MEPE-derived ASARM peptide inhibits odontogenic differentiation of dental pulp stem cells and impairs mineralization in tooth models of X-linked hypophosphatemia. [PDF]
PLoS ONE, 2013 Mutations in PHEX (phosphate-regulating gene with homologies to endopeptidases on the X-chromosome) cause X-linked familial hypophosphatemic rickets (XLH), a disorder having severe bone and tooth dentin mineralization defects.
Benjamin Salmon +17 more
doaj +1 more source
Presence and expression of hydrogenase specific C-terminal endopeptidases in cyanobacteria [PDF]
, 2003 BACKGROUND: Hydrogenases catalyze the simplest of all chemical reactions: the reduction of protons to molecular hydrogen or vice versa. Cyanobacteria can express an uptake, a bidirectional or both NiFe-hydrogenases.
Batur, Mehtap +2 more
core +3 more sources
Genetic divergence between populations of feral and domestic forms of a mosquito disease vector assessed by transcriptomics [PDF]
PeerJ, 2015 Culex pipiens, an invasive mosquito and vector of West Nile virus in the US, has two morphologically indistinguishable forms that differ dramatically in behavior and physiology. Cx.
Dana C. Price, Dina M. Fonseca
doaj +2 more sources
Family C1 cysteine proteases: Biological diversity or redundancy? [PDF]
, 2003 Recent progress in the identification and partial characterization of novel genes encoding cysteine proteases of the papain family has considerably increased our knowledge of this family of enzymes.
Brömme D. +4 more
core +1 more source
BMC Evolutionary Biology, 2011 Background Omptins are a family of outer membrane proteases that have spread by horizontal gene transfer in Gram-negative bacteria that infect vertebrates or plants.
Westerlund-Wikström Benita +3 more
doaj +1 more source
A biotechnology perspective of fungal proteases [PDF]
, 2015 Proteases hydrolyze the peptide bonds of proteins into peptides and amino acids, being found in all living organisms, and are essential for cell growth and differentiation.
Almeida, Renata Paula Coppini de +9 more
core +1 more source
Soluble ICAM-5, a product of activity dependent proteolysis, increases mEPSC frequency and dendritic expression of GluA1. [PDF]
PLoS ONE, 2013 Matrix metalloproteinases (MMPs) are zinc dependent endopeptidases that can be released from neurons in an activity dependent manner to play a role in varied forms of learning and memory.
Irina Lonskaya +8 more
doaj +1 more source
Using the SUBcellular database for Arabidopsis proteins to localize the Deg protease family
Frontiers in Plant Science, 2014 Sub-functionalization during the expansion of gene families in eukaryotes has occurred in part through specific subcellular localization of different family members.
Sandra Karin Tanz +7 more
doaj +1 more source