Results 11 to 20 of about 34,502 (251)
Molecular identification, characterization, and expression analysis of a serine protease inhibitor gene from cotton bollworm, Helicoverpa armigera (Lepidoptera: Noctuidae) [PDF]
Brazilian Journal of Biology, 2020 Serine protease inhibitors (serpins), a superfamily of protease inhibitors, are known to be involved in several physiological processes, such as development, metamorphosis, and innate immunity.
Muhammad Shakeel
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Scientific Reports, 2021 The Serine Protease Inhibitor (serpin) protein has been suggested to play a key role in the interaction of bifidobacteria with the host. By inhibiting intestinal serine proteases, it might allow bifidobacteria to reside in specific gut niches.
S. Duboux +6 more
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Pre-clinical evaluation of antiproteases as potential candidates for HIV-1 pre-exposure prophylaxis
Frontiers in Reproductive Health, 2022 Previous studies on highly HIV-1-exposed, yet persistently seronegative women from the Punwami Sex Worker cohort in Kenya, have shed light on putative protective mechanisms, suggesting that mucosal immunological factors, such as antiproteases, could be ...
Carolina Herrera +7 more
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Lentinan improved the efficacy of vaccine against Trichinella spiralis in an NLRP3 dependent manner.
PLoS Neglected Tropical Diseases, 2020 There is an urgent need for the development of new, improved vaccine adjuvants against T. spiralis infection. Polysaccharides are effective, safe, and biodegradable as adjuvant.
Xuemin Jin +7 more
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Journal of Translational Medicine, 2022 Background Helicobacter pylori (H. pylori) can disrupt the tight junctions between gastric epithelial cells and penetrate the intercellular spaces acting on epithelial cells, normal fibroblasts (NFs), and cancer-associated fibroblasts (CAFs), but their ...
Xueshu Chen +8 more
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Toxins, 2021 Hemostatic disorders are caused either by platelet-related dysfunctions, defective blood coagulation, or by a combination of both, leading to an increased susceptibility to cardiovascular diseases (CVD) and other related illnesses. The unique specificity
Hajer Aounallah +8 more
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Delving into Vertebrate Serpins for Understanding their Evolution [PDF]
, 2009 The superfamily of serine proteinase inhibitors (serpins) is involved in an array of fundamental biological processes such as blood coagulation, cell differentiation, cell migration, complement activation, embryo implantation, fibrinolysis, angiogenesis,
Abhishek Kumar
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An antibody that prevents serpin polymerisation acts by inducing a novel allosteric behavior [PDF]
, 2016 Serpins are important regulators of proteolytic pathways with an antiprotease activity that involves a conformational transition from a metastable to a hyperstable state. Certain mutations permit the transition to occur in the absence of a protease; when
Faull, Sarah V. +14 more
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JACC: Basic to Translational Science, 2017 Low-density lipoprotein receptor–related protein-1 (LRP1) is a ubiquitous membrane receptor functioning as a scavenger and regulatory receptor, inducing anti-inflammatory and prosurvival signals. Based on the known structure–activity of the LRP1 receptor
Stefano Toldo, PhD +9 more
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Serpins: the uncut version [PDF]
Structure, 1994 The structure of active antithrombin, the first active serpin to be solved, sheds new light on the conformational forms of this important class of inhibitor.
E J, Goldsmith, J, Mottonen
openaire +2 more sources