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Severe malaria

Malaria Journal, 2022
Severe malaria is a medical emergency. It is a major cause of preventable childhood death in tropical countries. Severe malaria justifies considerable global investment in malaria control and elimination yet, increasingly, international agencies, funders
Nicholas J. White
doaj   +4 more sources

Gut bacterial dysbiosis in pediatric severe malaria associates with post-discharge mortality [PDF]

Nature Communications
Gut microbiota have been implicated in severe malaria in murine models, but their contribution to the pathogenesis of severe malaria in children is unknown.
Olivia J. Bednarski, Sawyer B. Lehman, David Mzinza, Caroline Kazinga, Ruth Namazzi, Robert O. Opoka, Jie Ren, Tuan M. Tran, Terrie E. Taylor, Karl B. Seydel, Chandy C. John, Andrea L. Conroy, Nathan W. Schmidt   +12 more
doaj   +2 more sources

Pathology of Severe Malaria. [PDF]

Pathogens, 2023
Malaria, a devastating disease transmitted by mosquitoes, continues to plague many regions worldwide, affecting millions of lives annually [...]
Gallego-Delgado J.
europepmc   +4 more sources

Severe malaria intervention status in Nigeria: workshop meeting report [PDF]

Malaria Journal
Nigeria accounts for 39% of global malaria deaths in children under 5 years of age and the effective management of severe malaria is a health priority.
Emmanuel Shekarau, Miriam Uzoanya, Nnenna Ogbulafor, Severe Malaria Working Group   +3 more
doaj   +2 more sources

Severe malaria in children and adolescents in Southeast Gabon

BMC Infectious Diseases, 2023
Introduction Malaria remains a significant public health problem in sub-Saharan Africa. Child mortality due to severe malaria remains high in developing countries despite improvements in malaria management and a better understanding of its ...
Judicaël Boris Lendongo Wombo, Euloge Ibinga, Sandrine Lydie Oyegue-Liabagui, Roméo Karl Imboumy Limoukou, Alain Prince Okouga, Franck Mounioko, Sydney Maghendji-Nzondo, Jean Bernard Lekana-Douki, Edgard Brice Ngoungou   +8 more
doaj   +1 more source

Malaria Related Neurocognitive Deficits and Behavioral Alterations

Frontiers in Cellular and Infection Microbiology, 2022
Typical of tropical and subtropical regions, malaria is caused by protozoa of the genus Plasmodium and is, still today, despite all efforts and advances in controlling the disease, a major issue of public health. Its clinical course can present either as
Pamela Rosa-Gonçalves, Pamela Rosa-Gonçalves, Pamela Rosa-Gonçalves, Flávia Lima Ribeiro-Gomes, Flávia Lima Ribeiro-Gomes, Cláudio Tadeu Daniel-Ribeiro, Cláudio Tadeu Daniel-Ribeiro   +6 more
doaj   +1 more source

Shifts in the clinical epidemiology of severe malaria after scaling up control strategies in Mali

Frontiers in Neurology, 2022
A decrease in malaria incidence following implementation of control strategies such as use of artemisinin-based combination therapies, insecticide-impregnated nets, intermittent preventive treatment during pregnancy and seasonal malaria chemoprevention ...
Drissa Coulibaly, Abdoulaye K. Kone, Bourama Kane, Bouréima Guindo, Bourama Tangara, Mody Sissoko, Fayçal Maiga, Karim Traore, Aichatou Diawara, Amidou Traore, Ali Thera, Mahamadou S. Sissoko, Ogobara K. Doumbo, Mark A. Travassos, Mahamadou A. Thera   +14 more
doaj   +1 more source

A Comparative Study of Clinical Profiles of Vivax and Falciparum Malaria in Children at a Tertiary Care Centre in Uttarakhand [PDF]

Journal of Clinical and Diagnostic Research, 2013
Background: Falciparum malaria has been constantly associated with high morbidity and mortality for a long time. Vivax malaria, which was once thought to be a relatively benign condition, is appearing in its more malignant form, with severity ...
Ragini Singh, Shruti Kumar, S.K. Rana, Brijesh Thakur, S.P. Singh   +4 more
doaj   +1 more source

Treating severe malaria [PDF]

BMJ, 2005
Rectal artemether may be as good as intravenous quinine E very year over a million children die of malaria in Africa. In many settings, especially rural ones, most fatalities due to malaria occur outside hospital, although a substantial proportion of these children will have made contact with some level of healthcare in their final illness.1 Of those
Whitty, Christopher JM, Ansah, Evelyn, Reyburn, Hugh   +2 more
openaire   +3 more sources

NCR3 polymorphism, haematological parameters, and severe malaria in Senegalese patients [PDF]

PeerJ, 2018
Background Host factors, including host genetic variation, have been shown to influence the outcome of Plasmodium falciparum infection. Genome-wide linkage studies have mapped mild malaria resistance genes on chromosome 6p21, whereas NCR3-412 ...
Alassane Thiam, Sabrina Baaklini, Babacar Mbengue, Samia Nisar, Maryam Diarra, Sandrine Marquet, Mouhamadou Mansour Fall, Michel Sanka, Fatou Thiam, Rokhaya Ndiaye Diallo, Magali Torres, Alioune Dieye, Pascal Rihet   +12 more
doaj   +2 more sources